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Clifton Road NE, MS C-12
Atlanta, GA 30333
Phone: 1(404) 639-2416
Fax: 1(404) 639-3106 |
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| Integrated Disease Surveillance and Response |
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| Home > |
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Leprosy
| Introduction |
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The 44th World Health Assembly adopted the resolution WHA44.9 to eliminate leprosy as a public health problem (prevalence rate <1 case per 10 000 total population) at the global and regional levels by 2000. At the third International Conference in Abidjan, a Global Alliance for the Elimination of Leprosy was launched and a new target (2005) was proposed with the recommendation to eliminate leprosy at the national level in all countries worldwide. Multi drug therapy (MDT) is near 100% effective and case detection is relatively easy. Therefore, all should meet this target by 2005.
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| Guide for calculation of indicators |
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Prevalence and prevalence rate. Prevalence is the number of cases registered for MDT at a given point in time (on 31 December) and the prevalence rate is per 10 000 total population. The following types of patients are excluded from calculation of the prevalence rate: cured, defaulters, patients referred to other health centers, patients who are not on treatment for other reasons (died, transferred out). |
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Detection and detection rate. Number of cases newly detected in the period of the report and never treated before. The detection rate is per 100 000 total population. |
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Definitions of Disability Grade 0, 1, and 2. |
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For hands and feet: |
Grade 0 - |
no anesthesia, no visible deformity or damage. |
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Grade 1 - |
anesthesia but no visible deformity or damage. |
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Grade 2 - |
visible deformity or damage present. |
| For eyes: |
Grade 0 - |
no eye problems due to leprosy, no evidence of visual loss. |
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Grade 1 - |
eye problem due to leprosy present, but vision not severely affected as a result. |
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Grade 2 - |
severe visual impairment (vision worse than 6/60, inability to count fingers at 6 meters, lagopthalmos, iridocyclitis, and corneal opacities.) |
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Method of calculation of percentage with Grade 2 disability: number of new patients diagnosed with disability grade 2 divided by the number of all new patients diagnosed during the period of the report. |
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Cure rate. Number of patients who have received a complete treatment (6 blisters for PB patients and 12 blisters for MB patients) in a group of patients detected during a given period (six months before the report period for PB patients and one year for the MB patients). To facilitate the calculation of the average cure rate, it is recommended to take the same period of one year before the report period, as well as for PB and MB patients, divided by the number of patients detected in the selected period.
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| Analysis of time, place, and person. |
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Prevalence rate. If the prevalence rate is high (prevalence rate >1 per 10 000 population), this can indicate several possibilities: 1) high transmission in the district, 2) result of leprosy elimination campaigns, 3) result of over diagnosis, 4) result of recycling of old patients, or 5) standard MDT regimen is not followed, or low cure rate (accumulation of patients). |
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Detection rate. If the detection rate is high, the possibilities are the same as the first four above plus community awareness may be increasing. If the trend is decreasing, the following possibilities should be considered: 1) transmission is decreasing, 2) MDT services are becoming less active, or 3) image of leprosy has been damaged. Regarding 2) MDT services are becoming less active, it is natural to some extent that the detection decreases after intensified case finding activities like leprosy elimination campaigns. Review if the rest of the services are not deteriorating. Regarding 3) image of leprosy has been damaged, IEC
activities could have a negative impact on the image of leprosy. Review IEC materials and interview patients and the community. |
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Cure rate, defaulter rate. Cure rates should be as close to 100% as possible--it should be ensured that all patients registered for treatment are cured. Low cure rates, high defaulter rates and high proportion of patients still on treatment after having completed the standard regimen can indicate following problems: 1) MDT service not flexible. Improve service delivery to be more patient friendly, 2) Patient follow up is not satisfactory. Should improve follow up of irregular patients wherever possible, 3) patient is not well informed of importance of continuing MDT. Conduct proper patient education and counselling (see Guide for Health Professionals to Eliminate Leprosy as a Public Health Problem), and 4) MDT was not always available. Keep sufficient MDT stock and improve stock management. |
Reported New Leprosy Cases by Year, _____ - _____ |
________MB |
________PB |
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Yr 1 |
Yr 2 |
Yr 3 |
Yr 4 |
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1 |
2 |
3 |
4 |
MB Ad |
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MB Ch |
PB Ad |
PB Ch |
Leprosy Analysis and Quality of Surveillance Program
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Yr |
Yr |
Yr |
Yr |
PB |
MB |
PB |
MB |
PB |
MB |
PB |
MB |
| Elimination indicators |
| Prevalence |
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| Prevalence rate |
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| Detection |
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| Detection rate |
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| Patient care indicators |
| Proportion of children <15 yo among newly detected cases |
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| Proportion of cases with Grade 2 disabilities among newly detected cases |
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| Cure rate |
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| Managerial indicator |
| Proportion of health facilities providing MDT services |
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Date: June 30, 2005
Content source: Coordinating Center for Infectious Diseases / Division of Bacterial and Mycotic Diseases |
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