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Vaccine Safety Research

The United States’ long-standing vaccine safety system ensures vaccines are as safe as possible. As science advances and new information becomes available, this system will continue to improve.

Vaccine safety research:

  • Ensures the benefits of vaccines approved in the U.S. outweigh the risks.
  • Defines which groups should not certain vaccines.
  • Describes side effects and adverse events reported after vaccination.
  • Evaluates whether reported side effects and adverse events can be directly linked to a vaccine.

Vaccine Safety Publications

Access vaccine safety research conducted by CDC’s Immunization Safety Office (ISO).

The Health and Medicine Division of the National Academies Reports on Vaccine Safety

Read summaries of vaccine safety reports by the Institute of Medicine.

Archive: The Immunization Safety Office Scientific Agenda

Learn about the development of ISO’s scientific and research agenda.