Adult Immunization Schedule

Recommendations for Ages 19 Years or Older, United States, 2022

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¶ = Recommended vaccination for adults who meet age requirement, lack documentation of vaccination, or lack evidence of past infection
§ = Recommended vaccination for adults with an additional risk factor or another indication
± = Recommended vaccination based on shared clinical decision-making
⇒ = No recommendation/Not applicable

adult vaccine schedule
Vaccine 19-26 years 27-49 years 50-64 years ≥65 years
Influenza inactivated (IIV4) or
Influenza recombinant (RIV4) more info icon.
1 dose annually¶
more info icon.
Influenza live attenuated
(LAIV4) more info icon.
more info icon.
1 dose annually¶
Tetanus, diphtheria, pertussis
(Tdap or Td) more info icon.
1 dose Tdap each pregnancy; 1 dose Td/Tdap for wound management (see notes
1 dose Tdap, then Td or Tdap booster every 10 years¶
Measles, mumps, rubella
(MMR) more info icon.
1 or 2 doses depending on indication
(if born in 1957 or later)¶
Varicella
(VAR) more info icon.
2 doses
(if born in 1980 or later)¶
§ 2 doses§
Zoster recombinant
(RZV) more info icon.
2 doses for immunocompromising conditions (see notes 2 doses¶
Human papillomavirus
(HPV) more info icon.
2 or 3 doses depending on age at initial vaccination or condition¶ 27 through 45 years± ±
Pneumococcal
(PCV15, PCV20, PPSV23) more info icon.
1 dose PCV15 followed by PPSV23
OR
1 dose PCV20 (see notes
1 dose PCV15 followed by PPSV23
OR
1 dose PCV20¶
Hepatitis A
(HepA) more info icon.
2 or 3 doses depending on vaccine§
Hepatitis B
(HepB) more info icon.
2, 3, or 4 doses depending on vaccine or condition¶ § §
Meningococcal A, C, W, Y
(MenACWY) more info icon.
1 or 2 doses depending on indication, see notes for booster recommendations§
Meningococcal B
(MenB) more info icon.
§ 2 or 3 doses depending on vaccine and indication, see notes for booster recommendations§
19 through 23 years± § §
Haemophilus influenzae type b
(Hib) more info icon.
1 or 3 doses depending on indication§

Administer recommended vaccines if vaccination history is incomplete or unknown. Do not restart or add doses to vaccine series if there are extended intervals between doses. The use of trade names is for identification purposes only and does not imply endorsement by the ACIP or CDC.

Notes

For vaccine recommendations for persons 18 years of age or younger, see the Recommended Child and Adolescent Immunization Schedule.

Haemophilus influenzae type b vaccination

Hepatitis A vaccination

Hepatitis B vaccination

Human papillomavirus vaccination

Influenza vaccination

Measles, mumps, and rubella vaccination

Meningococcal vaccination

Pneumococcal vaccination

Tetanus, diphtheria, and pertussis (Tdap) vaccination

Varicella vaccination

Zoster vaccination

Vaccines in the Adult Immunization Schedule

adult vaccine schedule
Vaccines Abbreviations Trade names
Haemophilus influenzae type b Hib ActHIB®
Hiberix®
PedvaxHIB®
Hepatitis A vaccine HepA Havrix®
Vaqta®
Hepatitis A and hepatitis B vaccine HepA-HepB Twinrix®
Hepatitis B vaccine HepB Engerix-B®
Recombivax HB®
Heplisav-B®
Human papillomavirus vaccine HPV vaccine Gardasil 9®
Influenza vaccine, inactivated IIV  Many brands
Influenza vaccine, live, attenuated LAIV4 FluMist® Quadrivalent
Influenza vaccine, recombinant RIV4 Flublok Quadrivalent®
Measles, mumps, and rubella vaccine MMR M-M-R® II
Meningococcal serogroups A, C, W, Y vaccine MenACWY-D
MenACWY-CRM
MenACWY-TT
Menactra®
Menveo®
MenQuadfi®
Meningococcal serogroup B vaccine MenB-4C
MenB-FHbp
Bexsero®
Trumenba®
Pneumococcal 13-valent conjugate vaccine PCV13  Prevnar 13®
Pneumococcal 23-valent polysaccharide vaccine PPSV23  Pneumovax® 23
Tetanus and diphtheria toxoids Td Tenivac®
Tdvax™
Tetanus and diphtheria toxoids and acellular pertussis vaccine Tdap Adacel®
Boostrix®
Varicella vaccine VAR  Varivax®
Zoster vaccine, recombinant RZV  Shingrix

This schedule is recommended by the Advisory Committee on Immunization Practices  (ACIP) and approved by the Centers for Disease
Control and Prevention (CDC), American College of Physicians (ACPexternal icon), American Academy of Family Physicians (AAFPexternal icon), American College of Obstetricians and Gynecologists (ACOGexternal icon), American College of Nurse-Midwives (ACNMexternal icon), and American Academy of Physician Associates (AAPAexternal icon), and Society for Healthcare Epidemiology of America (SHEAexternal icon).

The comprehensive summary of the ACIP recommended changes made to the adult immunization schedule can be found in the February 18, 2022 MMWR.


Report

Injury Claims
All vaccines included in the adult immunization schedule except pneumococcal 23-valent polysaccharide (PPSV23) and zoster (RZV) vaccines are covered by the Vaccine Injury Compensation Program. Information on how to file a vaccine injury claim is available at www.hrsa.gov/vaccinecompensationexternal icon.

Questions or comments
Contact www.cdc.gov/cdc-info or 800-CDC-INFO (800-232-4636), in English or Spanish, 8 a.m.–8 p.m. ET, Monday through Friday, excluding holidays.

Helpful information


This schedule is recommended by the Advisory Committee on Immunization Practices  (ACIP) and approved by the Centers for Disease
Control and Prevention (CDC), American College of Physicians (ACPexternal icon), American Academy of Family Physicians (AAFPexternal icon), American College of Obstetricians and Gynecologists (ACOGexternal icon), American College of Nurse-Midwives (ACNMexternal icon), and American Academy of Physician Associates (AAPAexternal icon), and Society for Healthcare Epidemiology of America (SHEAexternal icon).

The comprehensive summary of the ACIP recommended changes made to the adult immunization schedule can be found in the February 18, 2022 MMWR.

Page last reviewed: February 17, 2022