Adult Immunization Schedule

Recommendations for Ages 19 Years or Older, United States, 2023

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¶ = Recommended vaccination for adults who meet age requirement, lack documentation of vaccination, or lack evidence of past infection
§ = Recommended vaccination for adults with an additional risk factor or another indication
± = Recommended vaccination based on shared clinical decision-making
⇒ = No recommendation/Not applicable

adult vaccine schedule
Vaccine 19-26 years 27-49 years 50-64 years ≥65 years
COVID-19 more info icon. 2- or 3- dose primary series and booster (see notes
Influenza inactivated (IIV4) or
Influenza recombinant (RIV4) more info icon.
¶1 dose annually OR¶
more info icon.
Influenza live attenuated
(LAIV4) more info icon.
1 dose annually¶
Tetanus, diphtheria, pertussis
(Tdap or Td) more info icon.
1 dose Tdap each pregnancy; 1 dose Td/Tdap for wound management (see notes
1 dose Tdap, then Td or Tdap booster every 10 years¶
Measles, mumps, rubella
(MMR) more info icon.
1 or 2 doses depending on indication
(if born in 1957 or later)¶
For healthcare personnel,
(see notes)⇒
Varicella
(VAR) more info icon.
2 doses
(if born in 1980 or later)¶
§ 2 doses§
Zoster recombinant
(RZV) more info icon.
2 doses for immunocompromising conditions (see notes 2 doses¶
Human papillomavirus
(HPV) more info icon.
2 or 3 doses depending on age at initial vaccination or condition¶ 27 through 45 years± ±
Pneumococcal
(PCV15, PCV20, PPSV23) more info icon.
1 dose PCV15 followed by PPSV23
OR
1 dose PCV20 (see notes
See Notes
See Notes±
Hepatitis A
(HepA) more info icon.
2, 3, or 4 doses depending on vaccine§
Hepatitis B
(HepB) more info icon.
2, 3, or 4 doses depending on vaccine or condition¶ § §
Meningococcal A, C, W, Y
(MenACWY) more info icon.
1 or 2 doses depending on indication, see notes for booster recommendations§
Meningococcal B
(MenB) more info icon.
§ 2 or 3 doses depending on vaccine and indication, see notes for booster recommendations§
19 through 23 years± § §
Haemophilus influenzae type b
(Hib) more info icon.
1 or 3 doses depending on indication§

Administer recommended vaccines if vaccination history is incomplete or unknown. Do not restart or add doses to vaccine series if there are extended intervals between doses. The use of trade names is for identification purposes only and does not imply endorsement by the ACIP or CDC.

Notes

For vaccine recommendations for persons 18 years of age or younger, see the Recommended Child and Adolescent Immunization Schedule.

COVID-19 vaccination

COVID-19 vaccination recommendations have changed. See the latest recommendations.

Haemophilus influenzae type b vaccination

Hepatitis A vaccination

Hepatitis B vaccination

Human papillomavirus vaccination

Influenza vaccination

Measles, mumps, and rubella vaccination

Meningococcal vaccination

Pneumococcal vaccination

Polio vaccination

Tetanus, diphtheria, and pertussis (Tdap) vaccination

Varicella vaccination

Zoster vaccination

Vaccines in the Adult Immunization Schedule*

adult vaccine schedule
Vaccine Abbreviation(s) Trade name(s)
COVID-19 vaccine 1vCOV-mRNA Comirnaty®/Pfizer- BioNTech COVID-19 Vaccine
SPIKEVAX®/Moderna COVID-19 Vaccine
2vCOV-mRNA Pfizer-BioNTech COVID-19 Vaccine, Bivalent
Moderna COVID-19 Vaccine, Bivalent
1vCOV-aPS Novavax COVID-19 Vaccine
Haemophilus influenzae type b vaccine Hib ActHIB®
Hiberix®
PedvaxHIB®
Hepatitis A vaccine HepA Havrix®
Vaqta®
Hepatitis A and hepatitis B vaccine HepA-HepB Twinrix®
Hepatitis B vaccine HepB Engerix-B®
Heplisav-B®
PreHevbrio®
Recombivax HB®
Human papillomavirus vaccine HPV Gardasil 9®
Influenza vaccine (inactivated) IIV4 Many brands
Influenza vaccine (live, attenuated) LAIV4 FluMist® Quadrivalent
Influenza vaccine (recombinant) RIV4 Flublok® Quadrivalent
Measles, mumps, and rubella vaccine MMR M-M-R II®
Priorix®
Meningococcal serogroups A, C, W, Y vaccine MenACWY-D Menactra®
MenACWY-CRM Menveo®
MenACWY-TT MenQuadfi®
Meningococcal serogroup B vaccine MenB-4C Bexsero®
MenB-FHbp Trumenba®
Pneumococcal conjugate vaccine PCV15 Vaxneuvance
PCV20 Prevnar 20
Pneumococcal polysaccharide vaccine PPSV23 Pneumovax 23®
Poliovirus vaccine IPV IPOL®
Tetanus and diphtheria toxoids Td Tenivac®
Tdvax™
Tetanus and diphtheria toxoids and acellular pertussis vaccine Tdap Adacel®
Boostrix®
Varicella vaccine VAR Varivax®
Zoster vaccine, recombinant RZV Shingrix

New vaccines added to the Schedule since February 2023 (See Addendum)

Vaccines Abbreviation(s) Trade name(s)
Respiratory Syncytial Virus vaccine RSV Arexvy®
ABRYSVO

*Administer recommended vaccines if vaccination history is incomplete or unknown. Do not restart or add doses to vaccine series if there are extended intervals between doses. The use of trade names is for identification purposes only and does not imply endorsement by the ACIP or CDC.

COVID-19, Poliovirus, and Influenza vaccines have new or updated ACIP recommendations. Please see Addendum for more details.


This schedule is recommended by the Advisory Committee on Immunization Practices  (ACIP) and approved by the Centers for Disease
Control and Prevention (CDC), American College of Physicians (ACP), American Academy of Family Physicians (AAFP), American College of Obstetricians and Gynecologists (ACOG), American College of Nurse-Midwives (ACNM), American Academy of Physician Associates (AAPA), American Pharmacists Association (APhA), and Society for Healthcare Epidemiology of America (SHEA).

The comprehensive summary of the ACIP recommended changes made to the adult immunization schedule can be found in the February 10, 2023 MMWR.