Alaska Invasive Bacterial Disease Surveillance Report Group B Streptococcus – 2015

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Background

AIP has conducted statewide surveillance of invasive group B Streptococcus (GBS) since 2000. Beginning in January 2007, invasive GBS became a reportable condition to the State of Alaska Division of Public Health (DPH).  Reports of cases of disease caused by this organism are shared between AIP and DPH.

Population

The population of the State of Alaska in 2015 was 737,625; 144,274 (19%) were Alaska Native people.  Source:  AK Dept. of Labor & Workforce Development population estimates.

Case Definition

An isolate of GBS from a normally sterile site that has been taken from a resident of Alaska.  Cases are also included when GBS has been isolated from a placenta and/or amniotic fluid with fetal demise.  Early-onset cases are in infants <7 days of age and late-onset are in infants 7-89 days of age.

Methods

Participating laboratories send isolates recovered from sterile sites to the AIP laboratory in Anchorage; materials and forms for isolate shipment and data collection are provided to each laboratory by AIP.  Demographic and clinical information on the cases are collected from a review of medical records.  Annually, AIP asks that each laboratory review their records and provide information on any cases that may have been overlooked.

Invasive group B Streptococcus, Early/Late Onset Cases & Rates by Race – Alaska, 2015

Alaska Native Non-Native
No. Cases Rate* No. Cases Rate*
Early onset 0 0 1 0.1
Late onset 2 0.7 3 0.4

*Cases per 1,000 live births

Invasive group B Streptococcus Cases by Race – Alaska, 2015

Race Cases n (%) Age Adjusted Rate* % Male Deaths n (%)
Alaska Native 15 (25) 11.1 73% 0 (0)
Non-Native† 44 (75)† 6.5 57% 4 (9.1)
Total 59 61% 4 (6.8)

*Cases per 100,000 per percent distribution of Alaska 2010 population
†Includes 7 cases for which race was unknown

Invasive group B Streptococcus, Cases & Rates by Age Group & Race – Alaska, 2015

Alaska Native Non-Native
Age (years) No. Cases Rate* No. Cases Rate*
<2 3 53.9 5 32
2-4 0 0 0 0
5-18 0 0 0 0
19-54 6 9 10 3.3
55-64 2 14.6 11 12.9
65+ 4 38.4 18 27.9
Total 15 10.4 44 7.4

*Cases per 100,000 population

Invasive group B Streptococcus, Clinical Presentations – Alaska, 2015

No. %*
Cellulitis 18 30
Bacteremia 17 29
Osteomyelitis 7 12
Septic arthritis 6 10
Pneumonia with bacteremia 4 7
Endocarditis 2 3
Meningitis 2 3
Amnionitis 1 2
Empyema 1 2
Peritonitis 1 2

*Percent of cases