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Appendix A: Search and Evidence Acquisition for the Guidance

The National Guideline Clearinghouse database was searched for current recommendations and guidelines using the keyword combinations:

  • (substance abusers OR drug users) AND (HIV prevention)
  • (substance abusers OR drug users) AND (Tuberculosis prevention OR TB prevention)
  • (substance abusers OR drug users) AND (sexually transmitted diseases prevention OR STDs prevention)
  • (substance abusers OR drug users) AND (Hepatitis C prevention OR viral hepatitis prevention)
  • (substance abusers OR drug users) AND (mental disorders prevention)

The MEDLINE_OVID search for the literature on integration was broken down into three sections each with MeSH and key words: disease or treatment (HIV, STD, TB, substance abuse, and mental disorder), drug use, integration (index term delivery of health care, integrated)

Disease or treatment

  1. HIV Infections/
  2. HIV infection$.ti,ab
  3. HIV infected.ti,ab
  4. Sexually Transmitted Diseases/
  5. Sexually Transmitted Diseases, Bacterial/
  6. Sexually Transmitted Diseases, Viral/
  7. Std$.ti,ab
  8. Sexually transmitted disease$.ti,ab
  9. Hepatitis, Viral, Human/
  10. Hepatitis C/
  11. Hepatitis B/
  12. HVC.ti,ab
  13. Hepatitis.ti,ab
  14. Tuberculosis/
  15. TB.ti,ab
  16. Substance abuse Treatment Centers/
  17. (Substance or drug$) adj2 (treat$).ti,ab
  18. OR/1–17

Drug use

  1. Substance Abuse, Intravenous/
  2. Heroin Dependence/
  3. Cocaine Related Disorders/
  4. Opioid-Related Disorders/
  5. Substance Related Disorders/
  6. Drug User/
  7. ((cocaine or heroin or crack or meth or opioid or inject$ methamphetamine or drug or substance) adj2 (abus$ OR addict$ OR use$ or dependence)).ti,ab
  8. (idu or idus or ivdu or ivdus).ti,ab.
  9. OR/19–26


  1. Delivery of Health Care, Integrated/
  2. Integrat$.ti,ab
  3. OR/28–29
  4. 18, 27, and 30
  5. Limit to 2000–2011

NOTE: No other limits applied.

Abbreviations: / = index term; ti = title; ab = abstract.

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