Table 1.2 – Hepatitis A: Cases & Rates by Demographics

Key points

During 2023, rates of reported cases of hepatitis A were highest among persons aged 30–39 years, males, Hispanic persons, persons living in urban areas, and in US Department of Health and Human Services Region 7 (Iowa, Kansas, Missouri, and Nebraska).
CDC 2023 Hepatitis A Surveillance Report

Numbers and rates* of reported cases† of hepatitis A, by demographic characteristics — United States, 2019–2023

Numbers and rates of reported cases of hepatitis A by demographic characteristics (age, sex, race/ethnicity, urbanicity, and US Department of Health and Human Services region) for 2019–2023. The first column lists the demographic characteristics. Each year has two columns of data; the first column indicates the number of reported hepatitis A cases, and the second column indicates the rate of reported hepatitis A cases for each demographic category.
Characteristic 2019 No. 2019 Rate* 2020 No. 2020 Rate* 2021 No. 2021 Rate* 2022 No. 2022 Rate* 2023 No. 2023 Rate*
Total§ 18,846 5.7 9,952 3.0 5,728 1.7 2,265 0.7 1,648 0.5
Age (years)
0–9 127 0.3 39 0.1 62 0.2 23 0.1 65 0.2
10–19 231 0.6 90 0.2 67 0.2 56 0.1 69 0.2
20–29 3,582 7.9 1,476 3.3 757 1.7 330 0.7 292 0.7
30–39 6,400 14.5 3,381 7.6 1,749 3.9 687 1.5 407 0.9
40–49 4,177 10.4 2,389 5.9 1,391 3.4 420 1.0 292 0.7
50–59 2,635 6.2 1,497 3.6 964 2.3 346 0.8 213 0.5
≥60 1,691 2.3 1,077 1.4 736 1.0 403 0.5 310 0.4
Sex
Male 11,824 7.3 6,141 3.8 3,594 2.2 1,472 0.9 1,034 0.6
Female 6,997 4.2 3,802 2.3 2,126 1.3 790 0.5 614 0.4
Race/ethnicity
American Indian/Alaska Native, non-Hispanic 60 2.2 56 2.0 27 1.1 25 1.0 7 0.3
Asian/Pacific Islander, non-Hispanic 139 0.7 92 0.4 87 0.4 98 0.5 147 0.7
Black, non-Hispanic 1,072 2.5 693 1.6 585 1.4 340 0.8 123 0.3
White, non-Hispanic 13,709 6.8 7,780 3.9 4,044 2.1 1,245 0.6 739 0.4
Hispanic 916 1.5 386 0.6 411 0.7 388 0.6 492 0.8
Other 617 n/a 216 n/a 138 n/a 57 n/a 77 n/a
Urbanicity
Urban 14,637 5.2 7,972 2.8 4,421 1.5 1,876 0.7 1,485 0.5
Rural 3,372 7.3 1,853 4.0 1,280 2.8 387 0.8 161 0.3
HHS region**
Region 1: Boston 593 4.0 240 1.6 94 0.6 104 0.7 109 0.7
Region 2: New York 1,001 3.5 412 1.5 318 1.1 125 0.4 169 0.6
Region 3: Philadelphia 1,611 5.2 836 2.7 542 1.7 300 1.0 208 0.7
Region 4: Atlanta 8,900 13.3 4,959 7.3 2,648 3.9 889 1.3 265 0.4
Region 5: Chicago 3,562 6.8 671 1.3 293 0.6 147 0.3 175 0.3
Region 6: Dallas 1,166 2.7 1,430 3.3 1,132 2.6 195 0.4 214 0.5
Region 7: Kansas City 393 2.8 679 4.8 502 3.5 206 1.4 131 0.9
Region 8: Denver 392 3.2 116 0.9 31 0.2 47 0.4 39 0.3
Region 9: San Francisco 943 1.8 276 0.5 127 0.2 194 0.4 292 0.6
Region 10: Seattle 285 2.0 333 2.3 41 0.3 58 0.4 46 0.3
 
Table 1.2 Data
table-1.2
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Source: CDC, National Notifiable Diseases Surveillance System.

* Rates per 100,000 population. Beginning in 2021, single-race population estimates are used for rate calculations. For prior years, bridged-race population estimates are used. When comparing the 2021 rates by race/ethnicity to prior years, differences may be due to the change in the denominator and should be interpreted with caution (see Technical Notes).

† Reported confirmed cases. For the case definition, see Acute Hepatitis A.

§ Numbers reported in each category may not add up to the total number of reported cases in a year due to cases with missing data.

Urbanicity was categorized according to the 2013 National Center for Health Statistics (NCHS) urban-rural classification scheme for counties and county-equivalent entities. Large central metro, large fringe metro, medium metro, and small metro counties were grouped as urban. Micropolitan and noncore counties were grouped as rural.

** US Department of Health and Human Services regions were categorized according to the grouping of states and US territories assigned under each of the 10 Health and Human Services regional offices. For the purposes of this report, regions with US territories (Region 2 and Region 9) contain data from states only.

n/a: Not applicable. Rate cannot be calculated due to lack of corresponding denominator.

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