What to know
Number of reported acute and chronic cases* of hepatitis C virus infection by case status — United States, 2021
| Acute Hepatitis C | Chronic Hepatitis C | |||
| State or Jurisdiction | Confirmed | Probable | Confirmed | Probable |
| Alabama | 110 | 19 | 4,273 | 3,346 |
| Alaska | N | N | 498 | 301 |
| Arizona | U | U | U | U |
| Arkansas | 44 | 17 | 2,189 | 1,560 |
| California† | 100 | 5 | 9,717 | 14,381 |
| Colorado | 3 | 2 | 1,737 | 949 |
| Connecticut | 36 | — | 809 | — |
| Delaware | 58 | 1 | 710 | 291 |
| District of Columbia | U | U | U | U |
| Florida | 1,545 | 264 | 9,130 | 3,776 |
| Georgia | 114 | 65 | 4,405 | 6,392 |
| Hawaii | — | — | U | U |
| Idaho | — | — | 669 | 827 |
| Illinois | 230 | 12 | 2,759 | 1,285 |
| Indiana | 179 | 18 | N | N |
| Iowa | 21 | — | 729 | 4 |
| Kansas | 2 | 26 | 647 | 1,270 |
| Kentucky | 198 | 113 | N | N |
| Louisiana | 308 | 1 | 3,634 | 1,188 |
| Maine | 134 | 34 | 704 | 870 |
| Maryland | 51 | 3 | 2,142 | 1,756 |
| Massachusetts | 161 | 11 | 2,346 | 1,461 |
| Michigan | 103 | 22 | 2,396 | 1,696 |
| Minnesota | 64 | 2 | 843 | 160 |
| Mississippi | 3 | 47 | 1,951 | — |
| Missouri | 11 | — | 4,267 | — |
| Montana | 26 | 3 | 684 | 356 |
| Nebraska | 10 | — | 414 | 261 |
| Nevada | 7 | — | 1,904 | 2,503 |
| New Hampshire | 3 | 14 | 47 | 82 |
| New Jersey | 88 | 6 | 2,366 | 2,604 |
| New Mexico | — | — | 288 | 121 |
| New York | 283 | 15 | 4,695 | 2,295 |
| North Carolina | 67 | 31 | N | N |
| North Dakota | — | — | 461 | 189 |
| Ohio | 126 | 27 | 6,661 | 5,471 |
| Oklahoma | 30 | 18 | 2,196 | 5,452 |
| Oregon | 21 | 7 | 1,657 | 2,097 |
| Pennsylvania | 158 | — | 6,891 | 4,090 |
| Rhode Island | U | U | U | U |
| South Carolina | 2 | 3 | 3,448 | 4,293 |
| South Dakota | 4 | — | 425 | 417 |
| Tennessee | 208 | 91 | 6,945 | 4,285 |
| Texas | 23 | 14 | N | N |
| Utah | 149 | 73 | 835 | 863 |
| Vermont | — | — | 307 | 68 |
| Virginia | 27 | 12 | 3,792 | 2,840 |
| Washington | 110 | 12 | 2,566 | 1,425 |
| West Virginia | 71 | 13 | 2,699 | 2,110 |
| Wisconsin | 133 | 4 | 1,385 | 522 |
| Wyoming | 2 | — | 319 | — |
| Total | 5,023 | 1,005 | 107,540 | 83,857 |
Source: CDC, National Notifiable Diseases Surveillance System.
* Confirmed and probable case definition available for Acute Hepatitis C and for Chronic Hepatitis C.
† California excludes chronic hepatitis C case counts from Los Angeles County (except for the City of Long Beach and the City of Pasadena) and San Diego County, geographic areas which include approximately 32% of California's total population.
—: No reported cases. The reporting jurisdiction did not submit any cases to CDC.
N: Not reportable. The disease or condition was not reportable by law, statue, or regulation in the reporting jurisdiction.
U: Unavailable. The data were unavailable.
Summary
For 2021, cases that meet both the confirmed and probable case definitions for acute hepatitis C and newly reported chronic hepatitis C are summarized to show the total burden of cases reported by jurisdictions to CDC.
The ability of a jurisdiction to apply the case definitions varies (see Technical Notes). Cases of probable hepatitis C require a positive test for antibodies to hepatitis C virus (anti-HCV) and an absence of other case definition criteria.
Therefore, it is unknown if cases represent current hepatitis C virus infection or a resolved hepatitis C virus infection. Jurisdictions without a public health reporting law or mandate for negative ribonucleic acid (RNA) test results will classify a positive anti-HCV test result as a probable case of hepatitis C.
Whereas jurisdictions with a public health reporting law or mandate for negative RNA test results will be more able to determine whether a positive anti-HCV test result is not a case (i.e., evidence of prior infection). For this reason, caution should be taken when comparing case counts for probable acute and chronic hepatitis C across jurisdictions.