OGPPH Publications


This page shows a list of yearly publications by the CDC Office of Genomics and Precision Public Health. For all publications in genomics in various CDC programs, please search our Public Health Genomics Knowledge Base.


1. Khoury MJ, Bedrosian S, Gwinn M, Little J, Ioannidis JP (eds). Human Genome Epidemiology (2nd ed.): Building the evidence for using genetic information to improve health and prevent disease. Oxford University Press, New York, 2010

2. Khoury MJ, Little J., Burke W (eds). Human Genome Epidemiology: A Scientific Foundation for Using Genetic Information to Improve Health and Prevent Disease. Oxford University Press, New York, 2004

3. Khoury MJ, Burke W, Thompson E (eds). Genetics and Public Health in the 21st Century: Using Genetic Information to Improve Health and Prevent Disease. Oxford University Press, New York, 2000

4. Muin J. Khoury, Terri H. Beaty and Bernice H. Cohen. Fundamentals of Genetic Epidemiologyexternal icon. Oxford University Press, New York, 1993


OGPPH Scientific Publications

Peer-reviewed scientific articles written by staff in CDC’s Office of Genomics and Precision Public Health and other researchers and public health professionals. You can perform a search of the CDC-Authored Genomics Publication Database of the Public Health Genomics Knowledge Base for specific topics.

  1. Allen CG, Green RF, Bowen S, Dotson WD, Yu Y, Khoury MJ. Challenges and Opportunities for Communication about the Role of Genomics in Public Healthexternal icon. Public Health Genomics. 2021 Jan 14;1-7.
  2. Barrios LC, Green RF, Honein MA. The Role of Testing in Reducing SARS-CoV-2 Transmission on College Campusesexternal icon. J Adolesc Health. 2021 Jan;68(1):1-2.
  3. Chang MH , Moonesinghe R, Truman BI. Racial and ethnic differences in COVID-19 hospitalizations by metropolitan status among Medicare beneficiaries, 1 January-31 December 2020external icon. J Public Health (Oxf). 2021 Oct 5;fdab355.
  4. Khoury MJ, Dotson WD. From genes to public health: are we ready for DNA-based population screening?external icon Genet Med. 2021 Mar 31.
  5. Khoury MJ, Holt KE. The impact of genomics on precision public health: beyond the pandemicexternal icon. Genome Med. 2021 Apr 23;13(1):67
  6. Wand H, Lambert SA, Tamburro C, Iacocca MA, O’Sullivan JW, Sillari C, Kullo IJ, Rowley R, Dron JS, Brockman D, Venner E, McCarthy MI, Antoniou AC, Easton DF, Hegele RA, Khera AV, Chatterjee N, Kooperberg C, Edwards K,  Vlessis K,  Kinnear K, Danesh JN,  Parkinson H,  Ramos EM,  Roberts MC, Ormond KE,  Khoury MJ,  Janssens ACJW,  Goddard KAB, Kraft P, MacArthur JAL, Inouye M,  Wojcik GL. Improving reporting standards for polygenic scores in risk prediction studiesexternal icon. Nature volume 591, pages 211–219 (2021)


  7. Allen CG, Peterson S, Khoury MJ, Brody LC, McBride CM. A scoping review of social and behavioral science research to translate genomic discoveries into population health impactexternal icon. Transl Behav Med. 2020 Sep 9;ibaa076.
  8. Allen CG, Roberts M, Andersen B, Khoury  MJ. Communication About Hereditary Cancers on Social Media: A Content Analysis of Tweets About Hereditary Breast and Ovarian Cancer and Lynch Syndromeexternal icon. J Cancer Educ. 2020 Feb;35(1):131-137.
  9. Green RF, Kumerow MT, Rodriguez JL, Addie S, Beachy SH, Senier L. Implementing Cancer Genomics in State Health Agencies: Mapping Activities to an Implementation Science Outcome Frameworkexternal icon. Public Health Genomics. 2020 Sep 17;1-12.
  10. Huang Y, Hui Q, Gwinn M, Hu Y, Quyyumi AA, Vaccarino V, Sun YV. Sexual Differences in Genetic Predisposition of Coronary Artery Diseaseexternal icon. Circ Genom Precis Med. 2020 Dec 17.
  11. Janssens ACJW, Gwinn M, Brockman 2JE, Powell K, Goodman M. Novel citation-based search method for scientific literature: a validation studyexternal icon. BMC Med Res Methodol. 2020 Feb 7;20(1):25
  12. Khoury MJ, Armstrong GL, Bunnell RE, Cyril J, Iademarco MF. The intersection of genomics and big data with public health: Opportunities for precision public health.external icon PLoS Med. 2020 Oct 29;17(10):e1003373.
  13. Murray MF, Evans JP, Khoury MJ. DNA-Based Population Screening – Potential Suitability and Important Knowledge Gapsexternal icon. JAMA 2020 Jan 28;323(4):307-308.
  14. Pearson TA, Califf RM, Roper R, Engelgau MM, Khoury MJ, Alcantara C, Blakely C, Boyce CA, Brown M, Croxton TL, Fenton K, Green Parker MC, Hamilton A, Helmchen L, Hsu LL, Kent DM, Kind A, Kravitz J, Papanicolaou GJ, Prosperi M, Quinn M, Price LN, Shireman PK, Smith SM, Szczesniak R, Goff DC Jr, Mensah GA. Precision Health Analytics With Predictive Analytics and Implementation Research: JACC State-of-the-Art Reviewexternal icon. J Am Coll Cardiol. 2020 Jul 21;76(3):306-320.
  15. Rasmussen SA, Khoury MJ, del Rio C. Precision Public Health as a Key Tool in the COVID-19 Responseexternal icon. JAMA. Published online August 12, 2020.
  16. Sigurdson M, Khoury MJ, Ioannidis JPA. Redundant Meta-Analyses Are Common in Genetic Epidemiologyexternal icon. J Clin Epidemiol. 2020 Jun 12;S0895-4356(19)30955-2.
  17. Srinivasan S, Won NY, Dotson WD, Wright ST, Roberts MC. Barriers and facilitators for cascade testing in genetic conditions: a systematic reviewexternal icon. Eur J Hum Genet. 2020 Sep 18.
  18. Yu W, Gwinn M, Khoury MJ. A New Resource for Genomics and Precision Health Information and Publications on the Investigation and Control of COVID-19 and other Coronaviruses.external icon BIORXIV. April 21, 2020


  19. Armstrong GL, MacCannell DR, Taylor J, Carleton HA, Neuhaus EB, Bradbury RS, Posey JE, Gwinn M. Pathogen Genomics in Public Health.external icon N Engl J Med. 2019 Dec 26;381(26):2569-2580.
  20. Auffray C, Griffin JL, Khoury MJ, Lupski JR, Schwab M. Ten years of Genome Medicine.external icon Genome Med. 2019 Feb 15;11(1):7.
  21. Engelgau MM, Khoury MJ, Roper RA, Curry JS, Mensah GA. Predictive Analytics: Helping Guide the Implementation Research Agenda at the National Heart, Lung, and Blood Institute.external icon Glob Heart. 2019 Mar;14(1):75-79.
  22. Green RF, Ari M, Kolor K, Dotson WD, Bowen S, Habarta N, Rodriguez JL, Richardson LC, Khoury MJ. Evaluating the role of public health in implementation of genomics-related recommendations: a case study of hereditary cancers using the CDC Science Impact Framework.external icon Genet Med. 2019 Jan;21(1):28-37.
  23. Gwinn M, MacCannell D, Armstrong GL. Next-Generation Sequencing of Infectious Pathogens.external icon JAMA. 2019 Feb 14.
  24. Hsu YY, Clyne M, Wei CH, Khoury MJ, Lu Z. Using deep learning to identify translational research in genomic medicine beyond bench to bedside.external icon Database (Oxford). 2019 Jan 1;2019.
  25. Kaphingst KA, Peterson E, Zhao J, Gaysynsky A, Elrick A, Hong SJ, Krakow M, Pokharel M, Ratcliff CL, Klein WMP, Khoury MJ, Chou WS. Cancer communication research in the era of genomics and precision medicine: a scoping review.external icon Genet Med. 2019 Aug;21(8):1691-1698.
  26. Khoury MJ. Precision Medicine vs Preventive Medicine.external icon JAMA. 2019 Jan 29;321(4):406.
  27. Lam TK, Lavigne JA, Qadir X, Khoury MJ, Schully SD. Training the Twenty-First Century Cancer Epidemiologist.external icon J Cancer Educ. 2019 Dec;34(6):1181-1189.
  28. Lee K, Clyne M, Yu W, Lu Z, Khoury MJ. Tracking human genes along the translational continuumexternal icon. Genom Med. 2019 Oct 16; 4(25)
  29. Mensah GA, Jaquish C, Srinivas P, Papanicolaou GJ, Wei GS, Redmond N, Roberts MC, Nelson C, Aviles-Santa L, Puggal M, Green Parker MC, Minear MA, Barfield W, Fenton KN, Boyce CA, Engelgau MM, Khoury MJ. Emerging Concepts in Precision Medicine and Cardiovascular Diseases in Racial and Ethnic Minority Populations.external icon Circ Res. 2019 Jun 21;125(1):7-13.
  30. Mensah GA, Yu W, Barfield WL, Clyne M, Engelgau MM, Khoury MJ. HLBS-PopOmics: an online knowledge base to accelerate dissemination and implementation of research advances in population genomics to reduce the burden of heart, lung, blood, and sleep disorders.external icon Genet Med. 2019 Mar;21(3):519-524.
  31. Mooneshinghe R, Yang Q, Zhang Z, Khoury MJ. Prevalence and Cardiovascular Health Impact of Family History of Premature Heart Disease in the United States: Analysis of the National Health and Nutrition Examination Survey, 2007–2014.external icon J Am Heart Assoc. 2019 Jul 16;8(14):e012364.
  32. Naber SK, Kundu S, Kuntz KM, Dotson WD, Williams MS, Zauber AG, Calonge N, Zallen DT, Ganiats TG, Webber EM, Goddard KA, Henrikson NB, van Bellegooijen M, Janssens AC, Lansdorp-Vogelaar I. Cost-effectiveness of risk-stratified colorectal cancer screening based on polygenic risk – current status and future potentialexternal icon. JNCI Cancer Spectrum 2019 October 14.
  33. Rasooly D, Ioannidis JPA, Khoury MJ, Patel CJ. Family History-Wide Association Study (“FamWAS”) for Identifying Clinical and Environmental Risk Factors for Common Chronic Diseases.external icon  Am J Epidemiol. 2019 Jun 7. pii: kwz125.
  34. Rivera DR ,  Lee JS, Hsu E, Khoury MJ, Meng F, Olivero O, Penberthy L, Tourassi GD, Harnessing the Power of Collaboration and Training Within Clinical Data Science to Generate Real‐World Evidence in the Era of Precision Oncologyexternal icon Clinical Pharmacology & Therapeutics 2019 June 5
  35. Roberts MC, Clyne M, Kennedy AE, Chambers DA, Khoury MJ. The current state of funded NIH grants in implementation science in genomic medicine: a portfolio analysis.external icon Genet Med. 2019 May;21(5):1218-1223.
  36. Roberts MC, Khoury MJ, Mensah GA. Perspective: The Clinical Use of Polygenic Risk Scores: Race, Ethnicity, and Health Disparities.external icon Ethn Dis.2019;29(3):513-516.
  37. Roberts MC, Mensah GA, Khoury MJ. Leveraging Implementation Science to Address Health Disparities in Genomic Medicine: Examples from the Field.external icon Ethn Dis. 2019 Feb 21;29(Suppl 1):187-192.


  38. Allen CG, Andersen B, Khoury MJ, Roberts MC. Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis.external icon  Public Health Genomics. 2018 Nov 22:1-7.
  39. Allen CG, Roberts M, Andersen B, Khoury MJ.  Communication About Hereditary Cancers on Social Media: A Content Analysis of Tweets About Hereditary Breast and Ovarian Cancer and Lynch Syndrome.external icon  J Cancer Educ. 2018 Dec 3.
  40. Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD. Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).external icon Circulation. 2018 Mar 26. pii: CIRCULATIONAHA.117.032321.
    visual abstract for Treating Familial Hypercholesterolemia to Prevent Heart Disease
  41. Chen Z, Kolor K, Grosse SD, Rodriguez JL, Lynch JA, Green RF, Dotson WD, Bowen MS, Khoury MJ. Trends in utilization and costs of BRCA testing among women aged 18-64 years in the United States, 2003-2014external icon. Genet Med. 2018 Apr;20(4):428-434.
  42. Feng LB, Grosse SD, Green RF, Fink AK, Sawicki GS. Precision Medicine In Action: The Impact Of Ivacaftor On Cystic Fibrosis–Related Hospitalizations.external icon Health Affairs. 2018 May
  43. Ioannidis JPA, Khoury MJ. Evidence Based Medicine and Big Genomic Data.external icon Hum Mol Genet. 2018 Feb 20.
  44. Khoury MJ, Bowen MS, Clyne M, Dotson WD, Gwinn ML, Green RF, Kolor K, Rodriguez JL, Wulf A, Yu W. From public health genomics to precision public health: a 20-year journey.external icon Genet Med. 2018 Jun;20(6):574-582.
  45. Khoury MJ, Engelgau M, Chambers DA, Mensah GA. Beyond Public Health Genomics: Can Big Data and Predictive Analytics Deliver Precision Public Health?external icon Public Health Genomics. 2018; 21(5-6):244-250.
  46. Khoury  M, Feero WG, Chambers DA, Brody LE, Aziz N, Green RC, Janssens AC, Murray MF, Rodriguez LL, Rutter JL, Schully SD, Winn DM, Mensah GA.  A collaborative translational research framework for evaluating and implementing the appropriate use of human genome sequencing to improve health.external icon PLoS Medicine, 2018 Aug 2.
  47. Lu CY, Williams MS, Ginsburg GS, Toh S, Brown JS, Khoury MJ. A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system.external icon Genet Med. 2018 Apr;20(4):390-396.
  48. Moonesinghe R, Beckles GLA, Liu T, Khoury MJ. The contribution of family history to the burden of diagnosed diabetes, undiagnosed diabetes, and prediabetes in the United States: analysis of the National Health and Nutrition Examination Survey, 2009-2014.external icon Genet Med. 2018 Jan 25
  49. Michael F. Murray, James P. Evans, Misha Angrist, Kee Chan,Wendy R. Uhlmann, Debra Lochner Doyle, Stephanie M. Fullerton, Theodore G. Ganiats, Jill Hagenkord, Sara Imhof, Sun Hee Rim, Leonard Ortmann, Nazneen Aziz, W. David Dotson, Ellen Matloff, Kristen Young, Kimberly Kaphingst, Angela Bradbury, Joan Scott, Catharine Wang, Ann Zauber, Marissa Levine, Bruce Korf, Debra G. Leonard, Catherine Wicklund, George Isham, Muin J. Khoury.  Proposed Approach for Implementing Genomics-Based Screening Programs for Healthy Adults. National Academy of Medicine,external icon Dec 3, 2018
  50. Peterson EB, Chou WS, Gaysynsky A, Krakow M, Elrick A, Khoury MJ, Kaphingst KA. Communication of cancer-related genetic and genomic information: A landscape analysis of reviews.external icon Transl Behav Med. 2018 Jan 29;8(1):59-70.
  51. Roberts MC, Dotson WD, DeVore CS, Bednar EM, Bowen DJ, Ganiats TG, Green RF, Hurst GM, Philp AR, Ricker CN, Sturm AC. Trepanier AM, Williams JL, Zierhut HA, Wilemon KA, Hampel H. Delivery Of Cascade Screening For Hereditary Conditions: A Scoping Review Of The Literature.external icon Health Affairs. 2018 May


  52. Berse B, Lynch JA, Bowen S, Grosse SD. In Reference to: “Cost and Utility of Thrombophilia Testing”.external icon  J Hosp Med. 2017 Sep;12(9):783.
  53. Goldfeder RL, Wall DP, Khoury MJ, Ioannidis JPA, Ashley EA. Human Genome Sequencing at the Population Scale: A Primer on High-Throughput DNA Sequencing and Analysis.external icon Am J Epidemiol. 2017 Oct 15;186(8):1000-1009.
  54. Gwinn M, MacCannell DR, Khabbaz RF. Integrating advanced molecular technologies into public health.external icon J Clin Microbiol. 2017 Mar;55(3):703-714.
  55. Khoury MJ. Editorial: Emergence of Gene-Environment Interaction Analysis in Epidemiologic Research.external icon Am J Epidemiol.. 2017 Oct 1;186(7):751-752.
  56. Khoury MJ. No Shortcuts on the Long Road to Evidence-Based Genomic Medicine.external icon JAMA. 2017 Jul 4;318(1):27-28.
  57. Khoury MJ, Galea S. Evaluating Precision Medicine’s Ability to Improve Population Health-Reply.external icon JAMA. 2017 Jan 24;317(4):441.
  58. Knowles JW, Rader DJ, Khoury MJ. Cascade Screening for Familial Hypercholesterolemia and the Use of Genetic Testing.external icon JAMA. 2017 Jul 25;318(4):381-382.
    visual abstract for Diagnosing Familial Hypercholesterolemia  early
  59. Kolor K, Chen Z, Grosse SD, Rodriguez JL, Green RF, Dotson WD, Bowen MS, Lynch JA, Khoury MJ. BRCA Genetic Testing and Receipt of Preventive Interventions Among Women Aged 18-64 Years with Employer-Sponsored Health Insurance in Nonmetropolitan and Metropolitan Areas – United States, 2009-2014.external icon MMWR Surveill Summ. 2017 Sep 8;66(15):1-11.
    visual abstract for Treating Familial Hypercholesterolemia to Prevent Heart Disease
  60. Lynch JA, Berse B, Bowen MS, Grosse SD. In Reference to: “Cost and Utility of Thrombophilia Testing”external icon J. Hosp. Med. 2017 September;12(9):783.
  61. Lynch JA, Berse B, Dotson WD, Khoury MJ, Coomer N, Kautter J. Utilization of genetic tests: analysis of gene-specific billing in Medicare claims data.external icon Genet Med. 2017 Aug;19(8):890-899.
  62. Qadir XV, Clyne M, Lam TK, Khoury MJ, Schully SD. Trends in published meta-analyses in cancer research, 2008-2013.external icon Cancer Causes Control. 2017 Jan;28(1):5-12.
  63. Phillips KA, Deverka PA, Sox HC, Khoury MJ, Sandy LG, Ginsburg GS, Tunis SR, Orlando LA, Douglas MP. Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.external icon Genet Med. 2017 Oct;19(10):1081-1091.
  64. Roberts MC, Kennedy AE, Chambers DA, Khoury MJ. The current state of implementation science in genomic medicine: opportunities for improvement.external icon Genet Med. 2017 Aug;19(8):858-863.


  65. Auffray C, Caulfield T, Griffin JL, Khoury MJ, Lupski JR, Schwab M. From genomic medicine to precision medicine: highlights of 2015.external icon Genome Med. 2016 Jan 29;8(1):12.
  66. Chambers DA, Feero WG, Khoury MJ. Convergence of Implementation Science, Precision Medicine, and the Learning Health Care System: A New Model for Biomedical Research.external icon JAMA. 2016 May 10;315(18):1941-2.
  67. Dotson WD, Bowen MS, Kolor K, Khoury MJ. Clinical utility of genetic and genomic services: context matters.external icon Genet Med. 2016 Jul;18(7):672-4.
  68. Grosse SD, Khoury MJ. Epidemiology matters: peering inside the “black box” in economic evaluations of genetic testing.external icon Genet Med. 2016 Oct;18(10):963-5.
  69. Iqbal SA, Wallach JD, Khoury MJ, Schully SD, Ioannidis JP. Reproducible Research Practices and Transparency across the Biomedical Literature.external icon PLoS Biol. 2016 Jan 4;14(1):e1002333.
  70. Kennedy AE, Khoury MJ, Ioannidis JP, Brotzman M, Miller A, Lane C, Lai GY, Rogers SD, Harvey C, Elena JW, Seminara D. The Cancer Epidemiology Descriptive Cohort Database: A Tool to Support Population-Based Interdisciplinary Research.external icon Cancer Epidemiol Biomarkers Prev. 2016 Oct;25(10):1392-1401.
  71. Khoury MJ, Galea S. Will Precision Medicine Improve Population Health?external icon JAMA. 2016 Oct 4;316(13):1357-1358.
  72. Khoury MJ, Iademarco MF, Riley WT. Precision Public Health for the Era of Precision Medicine.external icon Am J Prev Med. 2016 Mar;50(3):398-401.
  73. Khoury MJ. Announcement: National Family History Day – November 24, 2016.external icon MMWR Morb Mortal Wkly Rep. 2016 Nov 25;65(46):1305.
  74. Lynch JA, Berse B, Petkov V, Filipski K, Zhou Y, Khoury MJ, Hassett M, Freedman AN. Implementation of the 21-gene recurrence score test in the United States in 2011.external icon Genet Med. 2016 Oct;18(10):982-90.
  75. Marcus PM, Pashayan N, Church TR, Doria-Rose VP, Gould MK, Hubbard RA, Marrone M, Miglioretti DL, Pharoah PD, Pinsky PF, Rendle KA, Robbins HA, Roberts MC, Rolland B, Schiffman M, Tiro JA, Zauber AG, Winn DM, Khoury MJ. Population-based precision cancer screening: a symposium on evidence, epidemiology, and next steps.external icon Cancer Epidemiol Biomarkers Prev. 2016 Nov;25(11):1449-1455.
  76. Rodriguez JL, Thomas CC, Massetti GM, Duquette D, Avner L, Iskander J, Khoury MJ, Richardson LC. CDC Grand Rounds: Family History and Genomics as Tools for Cancer Prevention and Control.external icon MMWR Morb Mortal Wkly Rep. 2016 Nov 25;65(46):1291-1294.
  77. Valdez R, Grosse SD, Khoury MJ. The need for a next-generation public health response to rare diseases.external icon Genet Med. 2016 Oct 27;19(5):489-490
  78. Yu W, Gwinn M, Dotson WD, Green RF, Clyne M, Wulf A, Bowen S, Kolor K, Khoury MJ. A knowledge base for tracking the impact of genomics on population health.external icon Genet Med. 2016 Dec;18(12):1312-1314. 9.

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Page last reviewed: January 15, 2021