Medical Options for People with Familial Hypercholesterolemia

visual abstract for Treating Familial Hypercholesterolemia to Prevent Heart Disease

If you have familial hypercholesterolemia (FH), having a healthy lifestyle and being physically active are important, but often are not enough to lower your cholesterol to a healthy level. You will need to take cholesterol-lowering medicine to control your cholesterol levels. In most cases, you will need to take more than one type of cholesterol-lowering medicine to lower your LDL cholesterol to a healthy level.

The most commonly prescribed medicines are statins. For children diagnosed with FH, statin therapy in childhood may be required, often starting by age 8-10.

Other treatments for FH include:

If you have homozygous FH, you might need additional treatments to lower your LDL cholesterol, including:

These options all have risks and benefits and should be discussed with your doctor or lipid specialist to find out which ones are best for you.

If you or a family member have FH or high LDL cholesterol, it is important to maintain a healthy lifestyle along with taking your medicine. Making healthy lifestyle changes for your family can benefit your children who may be at risk for FH and promote healthy habits that they will continue as adults. The following are steps that you can take as a family:

Visit the CDC’s Division for Heart Disease and Stroke Prevention to learn more about what you can do to reduce your risk of getting heart disease.