Regional Cluster of New Delhi metallo-β-lactamase Carbapenemase-Producing Klebsiella pneumoniae — New York State, 2024–2025
- Presentation Day/Time: Tuesday, April 21, 1:55 PM
- Presenter: Daniel Baker, DNP, MPH, MS, EIS officer assigned to the New York State Department of Health
The Issue
- In November 2024, the New York State Department of Health (NYSDOH) identified six patients in a western New York nursing home with highly drug-resistant infections caused by carbapenemase-producing Klebsiella pneumoniae. Genetic testing identified 18 additional, closely related isolates from the same region collected beginning in spring 2024.
What We Did
- NYSDOH investigated to characterize the outbreak and limit transmission.
What We Found
- We identified 91 cases from patients in 24 facilities. Assessments of four hospitals and 19 nursing homes identified gaps in environmental cleaning, urinary catheter management, and hand hygiene.
What This Means
- This large, regional multifacility outbreak demonstrates potential for rapid regional spread of drug-resistant pathogens and was likely fueled by gaps in infection prevention and control practices. NYSDOH has started a regional initiative to disrupt transmission and limit infections.
