Module 2.7 – Wastewater-based variant tracking for SARS-CoV-2
Overview: This module describes the detection of SARS-CoV-2 RNA in municipal wastewater to provide early warning of increased community transmission and to inform clinical specimen selection for viral whole genome sequencing.
Posted: 11/17/21
Presenter: Brian Lowe, MPP (view bio)
Executive Director, Vermont Council on Rural Development
Further Reading
- National Wastewater Surveillance System (NWSS): A new public health tool to understand COVID-19 spread in a community.
CDC, 2021. - Public health interpretation and use of wastewater surveillance data.
CDC, 2021. - Wastewater tracking provides warning signs of local COVID-19 burdenexternal icon.
APHL Blog. - Droplet digital RT-PCR to detect SARS-CoV-2 variants of concern in wastewaterexternal icon.
Additional Resources
- Implementation of environmental surveillance for SARS-CoV-2 virus to support public health decisions: Opportunities and challengesexternal icon.
- Feasibility of neighborhood and building scale wastewater-based genomic epidemiology for pathogen surveillanceexternal icon.
Spurbeck, et al. Sci Total Environ, 2021. - COVID-19 containment on a college campus via wastewater-based epidemiology, targeted clinical testing and an interventionexternal icon.
Betancourt WQ, et al. Sci Total Environ, 2021. - Enumerating asymptomatic COVID-19 cases and estimating SARS-CoV-2 fecal shedding rates via wastewater-based epidemiologyexternal icon.
Schmitz BW, et al. medRxiv, 2021. - Wastewater-based epidemiology for tracking COVID-19 trend and variants of concern in Ohio, United Statesexternal icon.
Ai, et al. medRxiv, 2021. - The rapid assessment of aggregated wastewater samples for genomic surveillance of SARS-CoV-2 on a city-wide scaleexternal icon.
Rouchka, et al. medRxiv, 2021. - Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamicsexternal icon.
Nature Biotechnology, September 2020.
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Page last reviewed: November 17, 2021
Content source: Centers for Disease Control and Prevention