Module 2.5 – Confirming SARS-CoV-2 reinfection with whole genome sequencing

Overview: This module investigates a case study that demonstrates how whole genome sequencing can be used as an investigative tool to identify cases of true reinfection.

Posted: 08/27/21

Presenter: Megan Crumpler, PhD (view bio)
Laboratory Director
Orange County, CA Public Health Laboratory
Long Beach City, CA Public Health Laboratory

Download Presentation Slides pdf icon[PDF – 13 pages]

Further Reading:

1. Common investigation protocol for investigating suspected SARS-CoV-2 reinfection.
   CDC, 2020.

Additional Resources:

1. Genomic evidence for reinfection with SARS-CoV-2: a case studyexternal icon.
   Tillett, Lancet Infect Dis, 2021.
2. Severe acute respiratory syndrome coronavirus 2 reinfection cases corroborated by sequencingexternal icon.
   Massachi, et al. Am J Trop Med Hyg, 2021.
3. Assessment of the risk of SARS-CoV-2 reinfection in an intense re-exposure settingexternal icon.
   Abu-Raddad, et al. Clin Infect Dis, 2021.
4. SARS-CoV-2 sequence characteristics of COVID-19 persistence and reinfectionexternal icon.
   Choudhary, et al. Clin Infect Dis, 2021.