Module 2.2 – Healthcare cluster transmission

Overview: This module provides insight into two separate outbreaks at long-term care settings, and how sequencing helped clarify the pattern of transmission in these settings. You can read more about this work: Serial testing for SARS-CoV-2 and virus whole-genome sequencing

Posted: 01/08/21

Presenter: Nicholas Lehnertz, MD MPH MHS (view bio)
Physician and Epidemiologist, Minnesota Department of Health​

Download Presentation Slides pdf icon[PDF – 18 slides]

Further Reading:

1. Serial testing for SARS-CoV-2 and virus whole genome sequencing inform infection risk at two skilled nursing facilities with COVID-19 outbreaks – Minnesota, April-June 2020.
   Taylor, et al. MMWR, 2020.

Additional Resources:

1. Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study.external icon
   Meredith, et al. Lancet Infect Dis, 2020.
2. Genomic epidemiology and transmission dynamics of SARS-CoV-2 in congregate healthcare facilities in Santa Clara County, California.external icon
   MacCannell, et al. Clin Infect Dis, 2021.
3. Transmission of SARS-CoV-2 among healthcare workers and patients in a teaching hospital in the Netherlands confirmed by whole-genome sequencing.external icon
   Paltansing, et al. J Hosp Infect, 2021.
4. SARS-CoV-2 genomic variation in space and time in hospitalized patients in Philadelphia.external icon
   Everett, et al. mBio, 2021.
5. Viral sequencing reveals US healthcare personnel rarely become infected with SARS-CoV-2 through patient contact.external icon
   Braun, et al. Clin Infect Dis, 2021.
6. COVID-19 outbreak associated with a SARS-CoV-2 R.1 lineage variant in a skilled nursing facility after vaccination program — Kentucky, March 2021.
   Cavanaugh, et al. MMWR, 2021.
7. COVID-19 vaccine impact on rates of SARS-CoV-2 cases and post vaccination strain sequences among healthcare workers at an urban academic medical center: a prospective cohort study.external icon
   Bouton, et al. medRxiv, 2021.