Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis
|Affiliates||Stephen A Goutman , Orla Hardiman , Ammar Al-Chalabi , Adriano Chió , Masha G Savelieff , Matthew C Kiernan , Eva L Feldman 
 Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
|Summary||This research paper highlights the latest advances from the past 5 years pertaining to the complex genetics, pathophysiology, therapeutic development, and exposome science of amyotrophic lateral sclerosis. With the advances in genetic research and therapies, the paper suggests the future direction of applying gene profiling and genetic therapies to new clinical trials for ALS.|
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