Untargeted metabolomics yields insight into ALS disease mechanisms.

Affiliates	Stephen A Goutman [1], Jonathan Boss [2], Kai Guo [3], Fadhl M Alakwaa [1], Adam Patterson [1], Sehee Kim [2], Masha Georges Savelieff [1], Junguk Hur [3], Eva L Feldman [1] [1] Department of Neurology, University of Michigan [2] Department of Biostatistics, University of Michigan [3] Department of Biomedical Sciences, University of North Dakota
Journal	Neuromuscular
Summary	Understanding dysregulated metabolic pathways in amyotrophic lateral sclerosis (ALS) is important in discovering important therapeutic targets. This study located important metabolic pathway alterations with known pathomechanisms, or pathways to developing said disease, to ALS.
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Page last reviewed: November 18, 2021