A comparison of mercury exposure from seafood consumption and dental amalgam fillings in people with and without Amyotrophic Lateral Sclerosis (ALS): an International online case-control study

Affiliates Jane A. Parkin Kullmann [1], Roger Pamphlett [1,2]


[1] The Stacey Motor Neuron Disease Laboratory, Discipline of Pathology, Brain and Mind Centre, The University of Sydney
[2] Department of Neuropathology, Royal Prince Alfred Hospital

Journal International Journal of Environmental Research and Public Health
Summary Exposure to toxic heavy metals, like mercury, have been suggested to be risk factors for ALS. This study investigates the link between mercury exposure and ALS. Seafood is rich in mercury. Participants were asked about their seafood consumption in an online survey. This study found no evidence of an association between mercury exposures from eating seafood with risk of developing ALS. However, an exposure to mercury toxicity in ALS patients, such as genetic or epigenetic variations, multiple toxic metal interactions, or selenium deficiency, may be present.
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