Untargeted metabolomics yields insight into ALS disease mechanisms.

Affiliates Stephen A Goutman [1], Jonathan Boss [2], Kai Guo [3], Fadhl M Alakwaa [1], Adam Patterson [1], Sehee Kim [2], Masha Georges Savelieff [1], Junguk Hur [3], Eva L Feldman [1]


[1] Department of Neurology, University of Michigan
[2] Department of Biostatistics, University of Michigan
[3] Department of Biomedical Sciences, University of North Dakota

Journal Neuromuscular
Summary Understanding dysregulated metabolic pathways in amyotrophic lateral sclerosis (ALS) is important in discovering important therapeutic targets. This study located important metabolic pathway alterations with known pathomechanisms, or pathways to developing said disease, to ALS.
Link to paper Find the paper here!