Module 1.4 – Emerging variants of SARS-CoV-2

What to know

This module introduces basic concepts relevant to the emergence of new SARS-CoV-2 variants and the role of sequencing in their detection and definition.

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Module 1.4

Presenter: Michael Weigand, PhD | Bioinformatician, CDC
Download Presentation Slides [PDF – 16 slide]

Further Reading

  1. About variants of the virus that causes COVID-19. CDC.
  2. Genomic surveillance for SARS-CoV-2 variants. CDC.
  3. Tracking SARS-CoV-2 variants (WHO).
  4. The coronavirus is evolving before our eyes. Hamblin. The Atlantic, 2021.
  5. Coronavirus variants and mutations. Corum and Zimmer. New York Times, 2021.
  6. Genetic Variants of SARS-CoV-2—What Do They Mean? Lauring and Hodcroft. JAMA, 2021.

Additional Resources

  1. CoVariants.org.
  2. SARS-CoV-2 mutation situation reports. Scripps Research.
  3. PANGO lineage global reports.
  4. Pangolin COVID-19 lineage assigner. COG-UK.
  5. Spread of a SARS-CoV-2 variant through Europe in the summer of 2020. Hodcroft, et al. Nature, 2020.
  6. Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States. Alpert, et al. Cell, 2021.
  7. Linked Clusters of SARS-CoV-2 Variant B.1.351 — Maryland, January–February 2021.
  8. Emergence of a SARS-CoV-2 E484K variant of interest in Arizona. Skidmore, et al. medRxiv, 2021.
  9. Emergence of genomic diversity and recurrent mutations in SARS-CoV-2. van Dorp, et al. Infect Genet Evol, Sept 2020.
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Content Source:
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)