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Slide 21. Primary Isoniazid Resistance in U.S.-born vs. Foreign-born Persons, United States, 1993–2008. This graph shows primary isoniazid resistance in U.S.-born vs. foreign-born persons. Based on initial isolates from persons with no prior history of TB, the percentage of isoniazid resistance was approximately two times higher among foreign-born persons than among U.S.-born persons. In foreign-born persons, the percentage declined from 12.4% in 1993 to 10.3% in 2008. In U.S.-born persons, the percentage decreased from 6.8% in 1993 to 4.9% in 2008. Back to 2008 Surveillance Slides Main Page