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Nicotine

Synonyms & Trade Names
3-(1-Methyl-2-pyrrolidyl)pyridine
CAS No.
54-11-5
RTECS No.
QS5250000
DOT ID & Guide
1654 151
Formula
C5H4NC4H7NCH3
Conversion
IDLH
5 mg/m3
See: 54115
Exposure Limits
NIOSH REL
: TWA 0.5 mg/m3 [skin]
OSHA PEL
: TWA 0.5 mg/m3 [skin]
Measurement Methods

NIOSH 2544 , 2551
See: NMAM or OSHA Methods
Physical Description
Pale-yellow to dark-brown liquid with a fish-like odor when warm. [insecticide]
MW:
162.2
BP:
482°F (Decomposes)
FRZ:
-110°F
Sol:
Miscible
VP:
0.08 mmHg
IP:
8.01 eV
Sp.Gr:
1.01
Fl.P:
203°F
UEL:
4.0%
LEL:
0.7%
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities
Strong oxidizers, strong acids
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
nausea, salivation, abdominal pain, vomiting, diarrhea; headache, dizziness, hearing, visual disturbance; confusion, lassitude (weakness, exhaustion), incoordination; cardiac arrhythmias; convulsions, dyspnea (breathing difficulty); in animals: teratogenic effects
Target Organs
central nervous system, cardiovascular system, lungs, gastrointestinal tract, reproductive system
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH/OSHA

Up to 5 mg/m3:
(APF = 10) Any supplied-air respirator
(APF = 50) Any self-contained breathing apparatus with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION   See ICSC CARD: 0519   See MEDICAL TESTS: 0157
 
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