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Isophorone

Synonyms & Trade Names
Isoacetophorone; 3,5,5-Trimethyl-2-cyclohexenone; 3,5,5-Trimethyl-2-cyclo-hexen-1-one
CAS No.
78-59-1
RTECS No.
GW7700000
DOT ID & Guide
1993 128 (combustible liquid, n.o.s.)
Formula
C9H14O
Conversion
1 ppm = 5.65 mg/m3
IDLH
200 ppm
See: 78591
Exposure Limits
NIOSH REL
: TWA 4 ppm (23 mg/m3)
OSHA PEL
†: TWA 25 ppm (140 mg/m3)
Measurement Methods

NIOSH 2508 , 2556;
OSHA 7
See: NMAM or OSHA Methods
Physical Description
Colorless to white liquid with a peppermint-like odor.
MW:
138.2
BP:
419°F
FRZ:
17°F
Sol:
1%
VP:
0.3 mmHg
IP:
9.07 eV
Sp.Gr:
0.92
Fl.P:
184°F
UEL:
3.8%
LEL:
0.8%
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
Incompatibilities & Reactivities
Oxidizers, strong alkalis, amines
Exposure Routes
inhalation, ingestion, skin and/or eye contact
Symptoms
irritation eyes, nose, throat; headache, nausea, dizziness, lassitude (weakness, exhaustion), malaise (vague feeling of discomfort), narcosis; dermatitis; in animals: kidney, liver damage
Target Organs
Eyes, skin, respiratory system, central nervous system, liver, kidneys
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
Provide: Eyewash
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH

Up to 40 ppm:
(APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*
(APF = 10) Any supplied-air respirator*

Up to 100 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode*
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)*

Up to 200 ppm:
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)*
(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode*
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION   See ICSC CARD: 0169   See MEDICAL TESTS: 0123
 

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