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Isobutyronitrile

Synonyms & Trade Names
Isopropyl cyanide, 2-Methylpropanenitrile, 2-Methylpropionitrile
CAS No.
78-82-0
RTECS No.
TZ4900000
DOT ID & Guide
2284 131
Formula
(CH3)2CHCN
Conversion
1 ppm = 2.83 mg/m3
IDLH
N.D.
See: IDLH INDEX
Exposure Limits
NIOSH REL
: TWA 8 ppm (22 mg/m3)
OSHA PEL
: none
Measurement Methods

NIOSH 1606 (adapt)
See: NMAM or OSHA Methods
Physical Description
Colorless liquid with an almond-like odor. [Note: Forms cyanide in the body.]
MW:
69.1
BP:
219°F
FRZ:
-97°F
Sol:
Slight		 VP(130°F): 100 mmHg
IP:
?
Sp.Gr:
0.76
Fl.P:
47°F
UEL:
?
LEL:
?
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Incompatibilities & Reactivities
Oxidizers, reducing agents, strong acids & bases
Exposure Routes
inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
irritation eyes, skin, nose, throat; headache, dizziness, lassitude (weakness, exhaustion), confusion, convulsions; dyspnea (breathing difficulty); abdominal pain, nausea, vomiting
Target Organs
Eyes, skin, respiratory system, central nervous system, cardiovascular system
Personal Protection/Sanitation
(See protection codes)
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid
(See procedures)
Eye: Irrigate immediately
Skin: Soap flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations

NIOSH

Up to 80 ppm:
(APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)
(APF = 10) Any supplied-air respirator

Up to 200 ppm:
(APF = 25) Any supplied-air respirator operated in a continuous-flow mode
(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)

Up to 400 ppm:
(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)
(APF = 50) Any self-contained breathing apparatus with a full facepiece
(APF = 50) Any supplied-air respirator with a full facepiece

Up to 1000 ppm:
(APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode

Emergency or planned entry into unknown concentrations or IDLH conditions:
(APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus

Escape:
(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister
Any appropriate escape-type, self-contained breathing apparatus

Important additional information about respirator selection

See also: INTRODUCTION
 

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