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Malaria Information and Prophylaxis, by Country [M]

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CountryAreas with MalariaEstimated relative risk of Malaria for US Travelers2Drug Resistance3Malaria Species4Recommended Chemoprophlaxis5Key Information Needed and Helpful Links to Assess Need for Prophylaxis for Select Countries
Macau SAR (China)NoneNoneNot ApplicableNot ApplicableNot Applicable
MacedoniaNoneNoneNot ApplicableNot ApplicableNot Applicable
MadagascarAll areas, except rare cases in Antananarivo.ModerateChloroquineP. falciparum 85%
P. vivax 5-10%
P. ovale 5%

All areas except Antananarivo: Atovaquone-proguanil, doxycycline, or mefloquine

Antananarivo: Mosquito avoidance only.

Madeira Islands (Portugal)NoneNoneNot ApplicableNot ApplicableNot Applicable
MalawiAllModerateChloroquineP. falciparum 90%
P. malariae, P. ovale, and P. vivax 10% combined
Atovaquone-proguanil, doxycycline, or mefloquine
MalaysiaPresent in rural areas.LowChloroquineP. falciparum
P. vivax
P. malariae,
P. knowlesi,
and P. ovale.
Atovaquone-proguanil, doxycycline, or mefloquine
MaldivesNoneNoneNot ApplicableNot ApplicableNot Applicable
MaliAllHighChloroquineP. falciparum 85%
P. ovale 5-10%
P. vivax rare
Atovaquone-proguanil, doxycycline, or mefloquine
MaltaNoneNoneNot ApplicableNot ApplicableNot Applicable
Marshall IslandsNoneNoneNot ApplicableNot ApplicableNot Applicable
Martinique (France)NoneNoneNot ApplicableNot ApplicableNot Applicable
MauritaniaAll areas including the city of Nouakchott.HighChloroquineP. falciparum 85%
P. ovale 5-10%
P. vivax rare
Atovaquone-proguanil, doxycycline, or mefloquine
MauritiusNoneNoneNot ApplicableNot ApplicableNot Applicable
Mayotte (France)AllNo dataChloroquineP. falciparum 40-50%
P. vivax 35-40%
P. ovale <1%
Atovaquone-proguanil, doxycycline, or mefloquine

Present in Chiapas, Chihuahua, Durango, Nayarit, and Sinaloa.  Rare cases in Campeche, Jalisco, Oaxaca, Sonora, and Tabasco.  Rare cases in the municipality of Othon P. Blanco in the southern part of Quintana Roo bordering Belize. No malaria along the United States-Mexico border.

Very LowNoneP. vivax 100%

States of Chiapas, Chihuahua, Durango, Nayarit, and Sinaloa: Atovaquone-proguanil, chloroquine, doxycycline, mefloquine, or primaquine7

States of Campeche, Jalisco, Oaxaca, Sonora, Tabasco, and Othon P. Blanco municipality of Quintana Roo: Mosquito avoidance only


Micronesia, Federated States of; Includes: Yap Islands, Pohnpei, Chuuk, and KosraeNoneNoneNot ApplicableNot ApplicableNot Applicable
MoldovaNoneNoneNot ApplicableNot ApplicableNot Applicable
MonacoNoneNoneNot ApplicableNot ApplicableNot Applicable
MongoliaNoneNoneNot ApplicableNot ApplicableNot Applicable
MontenegroNoneNoneNot ApplicableNot ApplicableNot Applicable
Montserrat (U.K.)NoneNoneNot ApplicableNot ApplicableNot Applicable
MoroccoNoneNoneNot ApplicableNot ApplicableNot Applicable
MozambiqueAllModerateChloroquineP. falciparum 90%
P. malariae, P. ovale, and P. vivax rare
Atovaquone-proguanil, doxycycline, or mefloquine
  1. The information presented herein was accurate at the time of publication; however, factors that can change rapidly and from year to year, such as local weather conditions, mosquito vector density, and prevalence of infection, can markedly affect local malaria transmission patterns.
  2. This estimate of risk is based on numbers of cases of malaria reported in US travelers and the estimated volume of travel to these countries. In some instances the risk may be low because the actual intensity of transmission is low in that country. In other instances, significant malaria transmission may occur only in small focal areas of the country where US travelers seldom go. Thus even though the risk for the average traveler to that country may be low, the risk for the rare traveler going to the areas with higher transmission intensity will of course be higher. For some countries that are rarely visited by US travelers, there is insufficient information to make a risk estimate.
  3. Refers to P. falciparum malaria unless otherwise noted.
  4. Estimates of malaria species are based on best available data from multiple sources.
  5. Several medications are available for chemoprophylaxis. When deciding which drug to use, consider specific itinerary, length of trip, cost of drug, previous adverse reactions to antimalarials, drug allergies, and current medical history. All travelers should seek medical attention in the event of fever during or after return from travel to areas with malaria.
  6. This risk estimate is based largely on cases occurring in US military personnel who travel for extended periods of time with unique itineraries that likely do not reflect the risk for the average US traveler.
  7. Primaquine can cause hemolytic anemia in persons with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients must be screened for G6PD deficiency prior to starting primaquine. The U.S. Government's Official Web PortalDepartment of Health and Human Services
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