Malaria Information and Prophylaxis, by Country1 [C]
The information presented in this table is consistent with the information in the Health Information for International Travel 2010 (CDC's Yellow Book).
| Country | Areas with Malaria | Estimated relative risk of Malaria for US Travelers2 | Drug Resistance3 | Malaria Species4 | Recommended Chemoprophlaxis5 | Helpful links for Select Countries |
|---|---|---|---|---|---|---|
| Cambodia | Present throughout the country except none at the temple complex at Angkor Wat, Phnom Penh, and around Lake Tonle Sap | Moderate | Chloroquine Mefloquine (see map) |
P. falciparum 86% P. vivax 12% P. malariae 2% |
In the provinces of Preah Vihear, Siemreap, Odder Meanchey, Banteay Meanchey, Battambang, Pailin, Kampot, Koh Kong, and Pursat bordering Thailand: Atovaquone/proguanil or doxycycline All other areas with malaria: Atovaquone/proguanil, doxycycline, or mefloquine |
Administrative divisions of Cambodia |
| Cameroon | All | High | Chloroquine | P. falciparum 80% P. ovale 5-10% P. vivax rare |
Atovaquone/ proguanil, doxycycline, or mefloquine | |
| Canada | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Canary Islands (Spain) | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Cape Verde | Limited cases in Sao Tiago Island. | Very Low | Chloroquine | P. falciparum primarily | Mosquito avoidance | Map of Cape Verde |
| Cayman Islands (U.K.) | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Central African Republic | All | High | Chloroquine | P. falciparum 85% P. malariae, P. ovale, and P. vivax 15% |
Atovaquone/ proguanil, doxycycline, or mefloquine | |
| Chad | All | High | Chloroquine | P. falciparum 85% P. malariae, P. ovale, and P. vivax 15% |
Atovaquone/ proguanil, doxycycline, or mefloquine | |
| Chile | None | None | Not Applicable | Not Applicable | Not Applicable | |
| China | Rural parts of Anhui, Guizhou, Henan, Hubei, Hainan, and Yunnan provinces. Rare cases occur in other rural parts of the country below 1,500 m (4,921 ft) between May–December. None in urban areas. Some major river cruises may go through malaria endemic areas in Anhui and Hubei provinces. | Low | Chloroquine Mefloquine (see map) |
P. vivax primarily P. falciparum in select locations |
Along China-Burma border in the western part of Yunnan province: Atovaquone/proguanil or doxycyline Hainan and other parts of Yunnan province: Atovaquone/proguanil, doxycycline, or mefloquine Anhui, Guizhou, Henan, and Hubei provinces: Atovaquone/proguanil, chloroquine, doxycyline, mefloquine, or primaquine7 All other areas with malaria including river cruises that pass through malaria-endemic provinces: Mosquito avoidance |
Altitude information and to determine if a city is within a certain province Map of China |
| Christmas Island (Australia) | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Cocos (Keeling) Islands (Australia) | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Colombia | All areas <1,700 m (5,577 ft). None in Bogotá and Cartagena | Low | Chloroquine | P. falciparum 35–40% P. vivax 60–65% |
Atovaquone/ proguanil, doxycycline, or mefloquine | Altitude information for Colombia |
| Comoros | All | No data | Chloroquine | P. falciparum primarily | Atovaquone/ proguanil, doxycycline, or mefloquine | |
| Congo, (Republic of the, Brazzaville) | All | High | Chloroquine | P. falciparum 90% P. ovale 5-10% P. vivax rare |
Atovaquone/ proguanil, doxycycline, or mefloquine | |
| Congo, (Democratic Republic of the, Kinshasa) | All | No data | Chloroquine | P. falciparum 90% P. ovale 5-10% P. vivax rare |
Atovaquone/ proguanil, doxycycline, or mefloquine | |
| Cook Islands (New Zealand) | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Costa Rica | Limon province, but not in Limon city (Puerto Limon). Rare cases in other parts of the country. | Low | None | P. vivax 100% | Limon province: Atovaquone/proguanil, chloroquine, doxycycline, mefloquine, or primaquine7 All other areas: Mosquito avoidance |
Map of districts in Costa Rica To determine if a city is within a certain province |
| Côte d'Ivoire | All | High | Chloroquine | P. falciparum 85% P. ovale 5-10% P. vivax rare |
Atovaquone/ proguanil, doxycycline, or mefloquine | |
| Croatia | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Cuba | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Cyprus | None | None | Not Applicable | Not Applicable | Not Applicable | |
| Czech Republic | None | None | Not Applicable | Not Applicable | Not Applicable |
- The information presented herein was accurate at the time of publication; however, factors that can change rapidly and from year to year, such as local weather conditions, mosquito vector density, and prevalence of infection, can markedly affect local malaria transmission patterns. Updated information may be found on the CDC Travelers' Health website at www.cdc.gov/travel.
- This estimate of risk is based on numbers of cases of malaria reported in US travelers and the estimated volume of travel to these countries. In some instances the risk may be low because the actual intensity of transmission is low in that country. In other instances, significant malaria transmission may occur only in small focal areas of the country where US travelers seldom go. Thus even though the risk for the average traveler to that country may be low, the risk for the rare traveler going to the areas with higher transmission intensity will of course be higher. For some countries that are rarely visited by US travelers, there is insufficient information to make a risk estimate.
- Refers to P. falciparum malaria unless otherwise noted.
- Estimates of malaria species are based on best available data from multiple sources.
- Several medications are available for chemoprophylaxis. When deciding which drug to use, consider specific itinerary, length of trip, cost of drug, previous adverse reactions to antimalarials, drug allergies, and current medical history. All travelers should seek medical attention in the event of fever during or after return from travel to areas with malaria.
- This risk estimate is based largely on cases occurring in US military personnel who travel for extended periods of time with unique itineraries that likely do not reflect the risk for the average US traveler.
- Primaquine can cause hemolytic anemia in persons with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients must be screened for G6PD deficiency prior to starting primaquine.
