Antibiotic-Resistant Gonorrhea

Gonorrhea has progressively developed resistance to the antibiotic drugs prescribed to treat it. Following the spread of gonococcal fluoroquinolone resistance, the cephalosporin antibiotics have been the foundation of recommended treatment for gonorrhea. The emergence of cephalosporin-resistant gonorrhea would significantly complicate the ability of providers to treat gonorrhea successfully, since we have few antibiotic options left that are simple, well-studied, well-tolerated and highly effective. It is critical to continuously monitor antibiotic resistance in Neisseria gonorrhoeae and encourage research and development of new treatment regimens.


Gonococcal Isolate Surveillance Project (GISP) Profiles 2017 (April 2019)

AR Investment Map This interactive tool shows CDC’s key investments to combat antibiotic resistance (AR), including resistant gonorrhea, across the nation.

Success Stories
Cultivating Innovation in the Fight Against Antibiotic-Resistant Gonorrhea
CDC, the U.S. Food and Drug Administration (FDA), and the National Institutes of Health (NIH) collaborate to evaluate two untested combinations of antibiotics to treat gonorrhea.
Hawaii Success Story
Disease Intervention Specialists, STD clinic staff, and lab staff in Hawaii work together to identify and treat possible cases of drug-resistant gonorrhea.
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More STD Prevention Success Stories

Related Resources

ARG Infographic

ARG Infographics

Antibiotic Resistance Solutions Initiative

Antibiotic Resistance Solutions Initiative

AMD in Action - CDC responds to the urgent threat of antimicrobial-resistant gonorrhea. Learn more.

Advanced Molecular Detection (AMD)

Improving Antibiotic Use to Treat Gonorrhea

Improving Antibiotic Use to Treat Gonorrhea