Selenium hexafluoride (as Se)
Immediately Dangerous to Life or Health Concentrations (IDLH)
CAS number: 7783–79–1
NIOSH REL: 0.05 ppm (0.16 mg/m3) TWA
Current OSHA PEL: 0.05 ppm (0.4 mg/m3) TWA
1989 OSHA PEL: Same as current PEL
1993-1994 ACGIH TLV: 0.05 ppm (0.16 mg/m3) TWA
Description of substance: Colorless gas.
LEL :. . Nonflammable Gas
Original (SCP) IDLH: 5 ppm
Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by ACGIH  that 5 ppm for 4 hours resulted in pulmonary edema from which rabbits, guinea pigs, rats, and mice survived [Kimmerle 1960]; exposures to 10 ppm and greater for 4 hours were uniformly fatal to the exposed animals [Kimmerle 1960].
Short-term exposure guidelines: None developed
ACUTE TOXICITY DATA:
Lethal concentration data:
|Species||Reference||LC50(ppm)||LCLo(ppm)||Time||Adjusted 0.5-hrLC (CF)||Derived value|
|Kimmerle 1960Kimmerle 1960
|1 hr1 hr
|13 ppm (1.25)13 ppm (1.25)
13 ppm (1.25)
|1.3 ppm1.3 ppm
Other animal data: It has been reported that 5 ppm for 4 hours resulted in pulmonary edema from which rabbits, guinea pigs, rats, and mice survived [Kimmerle 1960].
Human data: None relevant for use in determining the revised IDLH.
|Revised IDLH: 2 ppmBasis for revised IDLH: The revised IDLH for selenium hexafluoride is 2 ppm based on acute inhalation toxicity data in animals [Kimmerle 1960].|
1. ACGIH . Selenium hexafluoride. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 226.
2. Kimmerle G . Vergleichende untersuchungen der inhalationstoxicitat von schwefel-, selen- und tellurhexafluorid (Comparative study of the inhalation toxicity of sulfur, selenium and tellurium hexafluorides). Arch Toxikol 18:140-144 (in German).