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Selenium hexafluoride (as Se)

May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)

CAS number: 7783–79–1

NIOSH REL: 0.05 ppm (0.16 mg/m3) TWA

Current OSHA PEL: 0.05 ppm (0.4 mg/m3) TWA

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 0.05 ppm (0.16 mg/m3) TWA

Description of substance: Colorless gas.

LEL :. . Nonflammable Gas

Original (SCP) IDLH: 5 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by ACGIH [1971] that 5 ppm for 4 hours resulted in pulmonary edema from which rabbits, guinea pigs, rats, and mice survived [Kimmerle 1960]; exposures to 10 ppm and greater for 4 hours were uniformly fatal to the exposed animals [Kimmerle 1960].

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

Species Reference LC50(ppm) LCLo(ppm) Time Adjusted 0.5-hrLC (CF) Derived value
RatMouse

G. pig

Kimmerle 1960Kimmerle 1960

Kimmerle 1960

———-

—–

1010

10

1 hr1 hr

1 hr

13 ppm (1.25)13 ppm (1.25)

13 ppm (1.25)

1.3 ppm1.3 ppm

1.3 ppm

Other animal data: It has been reported that 5 ppm for 4 hours resulted in pulmonary edema from which rabbits, guinea pigs, rats, and mice survived [Kimmerle 1960].

Human data: None relevant for use in determining the revised IDLH.

Revised IDLH: 2 ppmBasis for revised IDLH: The revised IDLH for selenium hexafluoride is 2 ppm based on acute inhalation toxicity data in animals [Kimmerle 1960].

REFERENCES:

1. ACGIH [1971]. Selenium hexafluoride. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 226.

2. Kimmerle G [1960]. Vergleichende untersuchungen der inhalationstoxicitat von schwefel-, selen- und tellurhexafluorid (Comparative study of the inhalation toxicity of sulfur, selenium and tellurium hexafluorides). Arch Toxikol 18:140-144 (in German).

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