Mercury compounds [except (organo) alkyls] (as Hg)
Immediately Dangerous to Life or Health Concentrations (IDLH)
CAS number: 7439–97–6 (Metal)
NIOSH REL: Hg Vapor: 0.05 mg/m3 TWA [skin];
Other: 0.1 mg/m3 CEILING [skin]
Current OSHA PEL: 0.1 mg/m3 CEILING
1989 OSHA PEL: Hg Vapor: 0.05 mg/m3 CEILING [skin];
Other non-alkyl compounds: 0.1 mg/m3 CEILING [skin]
1993-1994 ACGIH TLV: Hg Vapor: 0.05 mg/m3 TWA [skin];
Aryl & inorganic compounds: 0.1 mg/m3 TWA [skin]
Description of substance: Varies
Original (SCP) IDLH: 28 mg Hg/m3
Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by Patty  and AIHA  that “severe damage has been produced in the kidneys, liver, brain, heart, lungs, and colon of rabbits exposed for a single 4-hour period to mercury vapor at an average concentration of 28.8 mg/m3; mild damage to most of these organs occurred from 1 hour of exposure [Ashe et al. 1953].”
Existing short-term exposure guidelines: National Research Council [NRC 1984] Emergency Exposure Guidance Levels (EEGLs):
24-hour EEGL: 0.2 mg/m3
ACUTE TOXICITY DATA:
Lethal concentration data:
|Species||Reference||LC50||LCLo||Time||Adjusted 0.5-hrLC (CF)||Derived value|
|Hg Rabbit||Ashe et al. 1953||—–||29 mg/m3||30 hr||113 mg Hg/m3 (3.91)||11 mg Hg/m3|
Lethal dose data:
|Species||Reference||Route||LD50(mg/kg)||LDLo(mg/kg)||Adjusted LD||Derived value|
|Hg2Cl2Rat||Worthing 1991||oral||210||—–||1,250 mg Hg/m3||125 mg Hg/m3|
|HgCl2H2NRat||Trakhtenberg et al. 1981||oral||86||—–||482 mg Hg/m3||48 mg Hg/m3|
|HgCl2H2NMouse||Trakhtenberg et al. 1981||oral||68||—–||381 mg Hg/m3||38 mg Hg/m3|
Other animal data: Severe damage has been produced in the kidneys, lungs, and colon of rabbits exposed for a single 4-hour period to mercury vapor at an average of 28.8 mg/m3; mild damage to most of the organs occurred after 1 hour of exposure [Ashe et al. 1953].
Human data: None relevant for use in determining the revised IDLH.
|Revised IDLH: 10 mg Hg/m3Basis for revised IDLH: The revised IDLH for mercury compounds [except mercury (organo) alkyls] is 10 mg Hg/m3 based on acute inhalation toxicity data in animals [Ashe et al. 1953].|
1. AIHA . Mercury and its inorganic compounds (revised 1966). In: Hygienic guide series. Am Ind Hyg Assoc J 27:310-313.
2. Ashe WF, Largent EJ, Dutra FR, Hubbard DM, Blackstone M . Behavior of mercury in the animal organism following inhalation. AMA Arch Ind Hyg Occup Med 7:23-24.
3. NRC . Emergency and continuous exposure limits for selected airborne contaminants. Vol. 1. Washington, DC: National Academy Press, Committee on Toxicology, Board on Toxicology and Environmental Health Hazards, Commission on Life Sciences, National Research Council, pp. 89-94.
4. Patty FA, ed. . Industrial hygiene and toxicology. 2nd rev. ed. Vol. II. Toxicology. New York, NY: Interscience Publishers, Inc., p. 1094.
5. Trakhtenberg EM, Kozshun NN, et al. . New data on toxicity of inorganic compounds of mercury. Gig Tr Prof Zabol 25(7):27-30 (in Russian).
6. Worthing CR, ed. . Mercurous chloride. In: The pesticide manual. A world compendium. 9th ed. Farnham, Surrey, United Kingdom: The British Crop Protection Council, p. 552.
- Page last reviewed: December 4, 2014
- Page last updated: December 4, 2014
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