Sulfuryl fluoride

May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)

CAS number: 2699–79–8

NIOSH REL: 5 ppm (20 mg/m3) TWA, 10 ppm (40 mg/m3) STEL

Current OSHA PEL: 5 ppm (20 mg/m3) TWA

1989 OSHA PEL: 5 ppm (20 mg/m3) TWA, 10 ppm (40 mg/m3) STEL

1993-1994 ACGIH TLV: 5 ppm (21 mg/m3) TWA, 10 ppm (42 mg/m3) STEL

Description of substance: Colorless, odorless gas.

LEL: Nonflammable Gas

Original (SCP) IDLH: 1,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the report by Taxay [1966] that less than 5% mortality resulted from exposure of animals for 3 hours to 1,000 ppm.

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

Species Reference LC50(ppm) LCLo(ppm) Time Adjusted 0.5-hrLC (CF) Derived value
Rat Nitschke et al. 1986 991 —– 4 hr 1,982 ppm (2.0) 198 ppm
Mouse Truhaut et al. 1973 —– 1,200 1 hr 1,500 ppm (1.25) 150 ppm
Rabbit Truhaut et al. 1973 —– 5,000 1 hr 6,250 ppm (1.25) 625 ppm

Other animal data: It has been reported that less than 5% mortality resulted from exposure for 3 hours to 1,000 ppm [Taxay 1966].

Human data: None relevant for use in determining the revised IDLH.

REFERENCES:

1. Nitschke KD, Albee RR, Mattsson JL, Miller RR [1986]. Incapacitation and treatment of rats exposed to a lethal dose of sulfuryl fluoride. Fundam Appl Toxicol 7:664-670.

2. Taxay EP [1966]. Vikane inhalation. J Occup Med 8:425-426.

3. Truhaut R, Boudene C, Cluet JL [1973]. Toxicite de quelques derives gazeux fluores et oxyfluores du soufre. Arch Mal Prof 34(10-11):581-591 (in French).

Page last reviewed: December 4, 2014