Current Intelligence Bulletin 26: Niax® Catalyst ESN…. A Mixture of Dimethylamino -propionitrile and Bis(2-[dimethylamino)ethyl] ether

The purpose of this bulletin is to recommend that NIAX® Catalyst ESN and, its components, dimethylaminopropionitrile and bis[2-(dimethylamino)ethyl] ether, as well as formulations containing either component, be handled in the workplace as exceedingly hazardous materials. Investigations of outbreaks of urinary dysfunction among workers at a number of facilities that manufacture flexible polyurethane foam strongly suggest an association between NIAX® Catalyst ESN and the urological disorders. There is no current Federal standard for occupational exposure to NIAX® Catalyst ESN or either of its components. However, on April 7, 1978, the Occupational Safety and Health Administration issued a Health Hazard Alert and indicated “it is imperative that worker exposure to ESN and its components be completely avoided.”

Current Intelligence Bulletin 26: Niax® Catalyst ESN…. A Mixture of Dimethylamino -propionitrile and Bis(2-[dimethylamino)ethyl] ether