Methamphetamines - Method 9106
NIOSH Docket Number 176
Proposed NIOSH 9106 for Methamphetamine and Illicit Drugs, Precursors, and Adulterants by Liquid-Liquid Extraction and Gas Chromatography-Mass Spectrometry (GC/MS) is a sampling and analytical method that will be included in the NIOSH Manual of Analytical Methods, 5th edition. Two other proposed methamphetamine wipe methods will also be included. NIOSH 9109 is a Solid Phase Extraction Gas Chromatography-Mass Spectrometry (GC/MS) method and NIOSH 9111 is a Liquid Chromatography-Mass Spectrometry (LC/MS) method. NIOSH Method 9106 produces cleaner chromatograms and has longer operating times between mass spectrometer cleanings than NIOSH 9109 or NIOSH 9111. NIOSH 9109 has a quicker sample preparation time to run a larger number of samples, but has more problems with interferences than NIOSH 9106. NIOSH 9111 is the quickest and least expensive of the three methods, but has only been evaluated for the measurement of methamphetamine and not other illicit drugs of interest.
Material Under Consideration
Draft NIOSH document; (NIOSH Manual of Analytical Methods (NMAM) Fifth Edition; Methamphetamine and Illicit Drugs, Precursors, and Adulterants on Wipes by Liquid-Liquid Extraction) – 1/1/09pdf icon [PDF – 25,751 KB]
Submissions in order of Receipt
NIOSH responses to external review comments – 6/1/11pdf icon [PDF – 11,579 KB]