Since its inception in 2008, HPV-IMPACT has enabled CDC to describe trends in the cervical lesions that could progress to cancer and the reduction of vaccine-preventable cancer-causing HPV types (such as HPV16 and HPV18) in women diagnosed with these cervical lesions.
The Human Papillomavirus (HPV) Vaccine Impact Monitoring Project (HPV-IMPACT) is an ongoing surveillance project that determines rates of high-grade cervical lesions in women in the United States. High-grade cervical lesions are precancers that could progress to invasive cervical cancer if left untreated. The goal of HPV-IMPACT is to monitor the impact (such as reduction in HPV-related precancers) due to HPV vaccines. HPV-IMPACT was established in 2008 and includes defined areas in five states covering 1.5 million women. Data from HPV-IMPACT are used to monitor the impact (such as reduction in HPV-related precancers) of the HPV vaccination program in the United States.