Prevention Epicenters Publications and Findings

• Han JH, Nachamkin I, Coffin SE, Gerber JS, Fuchs B, Garrigan C, Han X, Bilker WB, Wise J, Tolomeo P, Lautenbach E; Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program. Use of a combination biomarker algorithm to identify medical intensive care unit patients with suspected sepsis at very low likelihood of bacterial infection. Antimicrob Agents Chemother. 2015 Aug 3. pii: AAC.00958-15.
• Hamilton KW, Gerber JS, Moehring R, Anderson DJ, Calderwood MS, Han JH, Mehta JM, Pollack LA, Zaoutis T, Srinivasan A, Camins BC, Schwartz DN, Lautenbach E; Centers for Disease Control and Prevention Epicenters Program. Point-of-prescription interventions to improve antimicrobial stewardship. Clin Infect Dis. 2015 Apr 15;60(8):1252-8. doi: 10.1093/cid/civ018. Epub 2015 Jan 16.
• Lin M, Weinstein R, and Hota B (2008). Delay of active antimicrobial therapy and mortality among patients with bacteremia: impact of severe neutropenia. Antimicrobial Agents Chemotherapy, 52(9): 3188-94.
• Camins B, King M, Wells J, Googe H, Patel M, Kourbatova E, Blumberg H (2009). Impact of an Antimicrobial Utilization Program on Antimicrobial Use at a Large Teaching Hospital: A Randomized Controlled Trial. Infection Control and Hospital Epidemiology, 30(10):931-938.
• Downes KJ, Weiss SL, Gerber JS, Klieger SB, Fitzgerald JC, Balamuth F, Kubis SE, Tolomeo P, Bilker WB, Han X, Nachamkin I, Garrigan C, Han JH, Lautenbach E, Coffin SE; Centers for Disease Control and Prevention Epicenters Program. A Pragmatic Biomarker-Driven Algorithm to Guide Antibiotic Use in the Pediatric Intensive Care Unit: The Optimizing Antibiotic Strategies in Sepsis (OASIS) Study.J Pediatric Infect Dis Soc. 2016 May 4. pii: piw023.
• Kelly BJ, Lautenbach E, Nachamkin I, Coffin SE, Gerber JS, Fuchs BD, Garrigan C, Han X, Bilker WB, Wise J, Tolomeo P, Han JH; Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program. Combined biomarkers discriminate a low likelihood of bacterial infection among surgical intensive care unit patients with suspected sepsis. Diagn Microbiol Infect Dis. 2016 Jan 8. pii: S0732-8893(16)00004-3. doi: 10.1016/j.diagmicrobio.2016.01.003. PMID:26971636

• Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R; CDC Prevention Epicenters Program; AHRQ DECIDE Network and Healthcare-Associated Infections Program. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med. 2013 Jun 13;368(24):2255-65.
• Caroff DA, Norris AH, Keller S, Vinnard C, Zeitler KE, Lukaszewicz J, Zborowski KA, Linkin DR; CDC Prevention Epicenters Program. Catheter salvage in home infusion patients with central line-associated bloodstream infection. Am J Infect Control. 2014 Dec;42(12):1331-3.
• Mayer J, Greene T, Howell J, Ying J, Rubin MA, Trick WE, Samore MH; CDC Prevention Epicenters Program. Agreement in classifying bloodstream infections among multiple reviewers conducting surveillance. Clin Infect Dis. 2012 Aug;55(3):364-70.
• Marschall J, Zhang L, Foxman B, Warren DK, Henderson JP; CDC Prevention Epicenters Program. Both host and pathogen factors predispose to Escherichia coli urinary-source bacteremia in hospitalized patients. Clin Infect Dis. 2012 Jun;54(12):1692-8.
• Hota B, Harting B, Weinstein RA, Lyles RD, Bleasdale SC, Trick W; Centers for Disease Control and Prevention Epicenters. Electronic algorithmic prediction of central vascular catheter use. Infect Control Hosp Epidemiol. 2010 Jan;31(1):4-11.
• Kidd KM, Sinkowitz-Cochran RL, Giblin TB, Tokars JI, Cardo DM, Solomon SL; Prevention Epicenters Program. Barriers to and facilitators of implementing an intervention to reduce the incidence of catheter-associated bloodstream infections. Infect Control Hosp Epidemiol. 2007 Jan;28(1):103-5.
• Climo M, Diekema D, Warren DK, Herwaldt LA, Perl TM, Peterson L, Plaskett T, Price C, Sepkowitz K, Solomon S, Tokars J, Fraser VJ, Wong E (2003, December). Prevalence of the use of central venous access devices within and outside of the intensive care unit: results of a survey among hospitals in the prevention epicenter program of the Centers for Disease Control and Prevention. Infection Control and Hospital Epidemiology, 24(12):942-5.
• Diekema DJ, Lee K, Raney P, Herwaldt LA, Doern GV, and Tenover FC (2004. Accuracy and Appropriateness of Antimicrobial Susceptibility Test Reporting for Bacteria Isolated from Blood Cultures. Journal of Clinical Microbiology, 42:2258-2260. DOI: 10.1128/JCM.42.5.2258-2260.2004.
• Lin MY, Weinstein RA, Hota B (2008). Delay of active antimicrobial therapy and mortality among patients with bacteremia: impact of severe neutropenia. Antimicrobial Agents Chemotherapy, 52(9):3188-94.

• Caroff DA, Edelstein PH, Hamilton K, Pegues DA; CDC Prevention Epicenters Program. The Bristol stool scale and its relationship to Clostridium difficile infection. J Clin Microbiol. 2014 Sep;52(9):3437-9.
• Kasper AM, Nyazee HA, Yokoe DS, Mayer J, Mangino JE, Khan YM, Hota B, Fraser VJ, Dubberke ER; Centers for Disease Control and Prevention Epicenters Program. A multicenter study of Clostridium difficile infection-related colectomy, 2000-2006. Infect Control Hosp Epidemiol. 2012 May;33(5):470-6.
• Dubberke ER, Butler AM, Nyazee HA, Reske KA, Yokoe DS, Mayer J, Mangino JE, Khan YM, Fraser VJ; Centers for Disease Control and Prevention Epicenters Program. The impact of ICD-9-CM code rank order on the estimated prevalence of Clostridium difficile infections. Clin Infect Dis. 2011 Jul 1;53(1):20-5.
• Dubberke ER, Butler AM, Yokoe DS, Mayer J, Hota B, Mangino JE, Khan YM, Popovich KJ, Stevenson KB, McDonald LC, Olsen MA, Fraser VJ; Prevention Epicenters Program of the Centers for Disease Control and Prevention. Multicenter study of surveillance for hospital-onset Clostridium difficile infection by the use of ICD-9-CM diagnosis codes. Infect Control Hosp Epidemiol. 2010 Mar;31(3):262-8.
• Dubberke ER, Butler AM, Reske KA, Agniel D, Olsen MA, D’Angelo G, McDonald LC, Fraser VJ (2008). Attributable Outcomes of Endemic Clostridium difficile-associated Disease in Nonsurgical Patients. Emerging Infectious Diseases, 14 (7):1031-8.
• Dubberke E, Butler A, Hota B, Khan Y, Mangino J, Mayer J, Popovich K, Stevenson K, Yokoe D, McDonald C, Jernigan J, Fraser V (2009). Multicenter study of the impact of community-onset Clostridium difficile infection on surveillance for Clostridium difficile infection. Infection Control and Hospital Epidemiology, 30(6):518-25.
• Litvin M, Reske K, Mayfield J, McMullen K, Georgantopoulos P, Copper S, Hoppe-Bauer J, Fraser V, Warren D, Dubberke E (2009). Identification of a Pseudo-Outbreak of Clostridium difficile Infection (CDI) and the Effect of Repeated Testing, Sensitivity, and Specificity on Perceived Prevalence of CDI. Infection Control and Hospital Epidemiology, 20:1166-1171.
• Dubberke E, McMullen K, Mayfield J, Reske K, Georgantopoulos P, Warren D, Fraser V (2009). Hospital-associated Clostridium difficile Infection: Is It Necessary to Track Community-Onset Disease? Infection Control and Hospital Epidemiology, 30:332-
• Dubberke ER, Reske KA, Olsen MA, McDonald LC, Fraser VJ (2008). Short and Long-Term Attributable Costs of Clostridium difficile-associated Disease in Nonsurgical Inpatients. Clinical Infectious Diseases, 46:497-504. DOI: 10.1086/526530.
• Dubberke ER, Wertheimer AI (2009). Review of Current Literature on the Economic Burden of Clostridium difficile Infection. Infection Control and Hospital Epidemiology, 30(1):57–66.
• Sohn S, Climo M, Diekema D, Fraser V, Herwaldt L, Marino S, Noskin G, Perl T, Song X, Tokars J, Warren D, Wong E, Yokoe DS, Zembower T, Sepkowitz KA, and Prevention Epicenter Hospitals. (2005, August). Varying rates of Clostridium difficile-associated diarrhea at prevention epicenter hospitals. Infection Control and Hospital Epidemiology, 26(8):676-9.

• Shimasaki T, Segreti J, Tomich A, Kim J, Hayden MK, Lin MY, CDC Prevention Epicenters Program. Active screening and interfacility communication of carbapenem-resistant Enterobacteriaceae (CRE) in a tertiary-care hospital. Infect Control Hosp Epidemiol. 2018 Jul 19:1-5.
• Hayden MK, Lin MY, Lolans K, Weiner S, Blom D, Moore NM, Fogg L, Henry D, Lyles R, Thurlow C, Sikka M, Hines D, Weinstein RA; Centers for Disease Control and Prevention Epicenters Program. Prevention of colonization and infection by Klebsiella pneumoniae carbapenemase-producing enterobacteriaceae in long-term acute-care hospitals. Clin Infect Dis. 2015 Apr 15;60(8):1153-61.
• Han JH, Johnston B, Nachamkin I, Tolomeo P, Bilker WB, Mao X, Clabots C, Lautenbach E, Johnson JR; CDC Prevention Epicenters Program. Clinical and molecular epidemiology of Escherichia coli sequence type 131 among hospitalized patients colonized intestinally with fluoroquinolone-resistant E. coli. Antimicrob Agents Chemother. 2014 Nov;58(11):7003-6.
• Knelson LP, Williams DA, Gergen MF, Rutala WA, Weber DJ, Sexton DJ, Anderson DJ; Centers for Disease Control and Prevention Epicenters Program. A comparison of environmental contamination by patients infected or colonized with methicillin-resistant Staphylococcus aureus or vancomycin-resistant enterococci: a multicenter study. Infect Control Hosp Epidemiol. 2014 Jul;35(7):872-5.
• Calderwood MS, Desjardins CA, Sakoulas G, Nicol R, Dubois A, Delaney ML, Kleinman K, Cosimi LA, Feldgarden M, Onderdonk AB, Birren BW, Platt R, Huang SS; CDC Prevention Epicenters Program. Staphylococcal enterotoxin P predicts bacteremia in hospitalized patients colonized with methicillin-resistant Staphylococcus aureus. J Infect Dis. 2014 Feb 15;209(4):571-7.
• Khair HN, VanTassell P, Henderson JP, Warren DK, Marschall J; CDC Prevention Epicenters Program. Vancomycin resistance has no influence on outcomes of enterococcal bacteriuria. J Hosp Infect. 2013 Nov;85(3):183-8.
• Lin MY, Lyles-Banks RD, Lolans K, Hines DW, Spear JB, Petrak R, Trick WE, Weinstein RA, Hayden MK; Centers for Disease Control and Prevention Epicenters Program. The importance of long-term acute care hospitals in the regional epidemiology of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae. Clin Infect Dis. 2013 Nov;57(9):1246-52.
• Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R; CDC Prevention Epicenters Program; AHRQ DECIDE Network and Healthcare-Associated Infections Program. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med. 2013 Jun 13;368(24):2255-65.
• Prabaker K, Lin MY, McNally M, Cherabuddi K, Ahmed S, Norris A, Lolans K, Odeh R, Chundi V, Weinstein RA, Hayden MK; Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program. Transfer from high-acuity long-term care facilities is associated with carriage of Klebsiella pneumonia carbapenemase-producing Enterobacteriaceae: a multihospital study. Infect Control Hosp Epidemiol. 2012 Dec;33(12):1193-9.
• Hota B, Lyles R, Rim J, Popovich KJ, Rice T, Aroutcheva A, Weinstein RA; CDC Prevention Epicenters. Predictors of clinical virulence in community-onset methicillin-resistant Staphylococcus aureus infections: the importance of USA300 and pneumonia. Clin Infect Dis. 2011 Oct;53(8):757-65.
• Climo M, Sepkowitz K, Zuccotti G, Fraser V, Warren D, Perl T, Speck K, Jernigan J, Bush A, Wong E (2009). Daily Bathing with Chlorhexidine Reduces the Acquisition of Methicillin- resistant Staphylococcus aureus, Vancomycin-Resistant Enterococci, and Healthcare- associated Bloodstream Infections: Results of a Multicenter Trial. Critical Care Medicine, 37(6):1858-65
• Data R, Huang, SS (2008). Risk of Infection and Death due to Methicillin-resistant Staphylococcus aureus in Long-term Carriers. Clinical Infectious Diseases, 47(2):176-81.
• Evans RS, Wallace CJ, Lloyd JF, Taylor CW, Abouzelof RH, Sumner S, Johnson KW, Wuthrich A, Harbarth S, Samore MH (2008). Rapid Identification of Hospitalized Patients at High Risk for MRSA Carriage. Journal of the American Medical Informatics Association, 15(4): 506-512. DOI:10.1197/jamia.M2721.
• Hota B, Ellenbogen C, Hayden M, Aroutcheva A, Rice T, Weinstein R (2007). Community associated Methicillin-resistant Staphylococcus aureus skin and soft tissue infections at a public hospital: do public housing and incarceration amplify transmission? Archives of Internal Medicine, 167(10): 1026-33.
• Huang SS, Rifas-Shiman SL, Warren DK, Fraser VJ, Climo MW, Wong ES, Cosgrove SE, Perl TM, Pottinger JM, Herwaldt LA, Jernigan JA, Tokars JL, Diekema DJ, Hinrichsen VL, Yokoe DS, Platt R (2007, February). Improving Methicillin-resistant Staphylococcus aureus Surveillance and Reporting in Intensive Care Units. Journal of Infectious Diseases, 195(3):330-8.
• Huang SS, Platt R (2003, February). Risk of Methicillin-resistant Staphylococcus aureus infection after previous infection or colonization. Journal of Clinical Infectious Diseases, 36(3):281-5.
• Huang SS, Diekema D, Warren D, Zuccotti G, Winokur P, Tendolkar S, Ward M, Datta R, Jones R, Boyken L, Aubrey T, Onderdone A, Platt R (2008). Strain-relatedness of Methicillin-resistant Staphylococcus aureus isolates from patients with repeated infection. Clinical Infectious Diseases, 46(8):1241-7.
• McMullen K, Warren D, Woeltje K (2009). The Changing Susceptibilities of Methicillin-resistant Staphylococcus aureusat a Midwestern Hospital: The Emergence of “Community- Associated” MRSA. American Journal of Infection Control, 37(6):454-7.
• Popovich K (2009). Staphylococcus aureus: Not Always Right Under Your Nose. Infection Control and Hospital Epidemiology, 30(8):272-729.
• Popovich K, Hota B (2008). The Treatment and Prevention of Community-associated methicilin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections. Dermatological Therapy, 21(3):167-79, 1396-0296.
• Popovich K, Hota B, Weinstein R (2008). Treatment of Community-associated Methicillin-resistant Staphylococcus aureus. Current Infection Diseases, 9(5):398-407. Current Infectious Disease Report, 10(5):411-20.
• Popvich K, Hota B, Rice T, Aroutcheva A, Weinstein R (2007).Phenotypic Prediction Rule for Community-associated Methicillin-resistant Staphylococcus aureus. Journal of Clinical Microbiology, 45(7) :2293-5.
• Popovich K, Weinstein R (2009). The Graying of Methicillin-resistant Staphylococcus aureus. Infection Control and Hospital Epidemiology, 30(1):9-12.
• Popovich KJ, Weinstein RA, and Hota B (2008). Are community-associated Methicillin-resistant Staphylococcus aureus (MRSA) strains replacing traditional nosocomial MRSA strains? Clinical Infectious Diseases, 46(6):787-94.
• Huang SS, Rifas-Shiman SL, Pottinger JM, Herwaldt LA, Zembower TR, Noskin GA, Cosgrove SE, Perl TM, Curtis AB, Tokars JL, Diekema DJ, Jernigan JA, Hinrichsen VL, Yokoe DS, Platt R; Centers for Disease Control and Prevention Epicenters Program. Improving the assessment of vancomycin-resistant enterococci by routine screening. J Infect Dis. 2007 Feb 1;195(3):339-46.
• Trick WE, Lin MY, Cheng-Leidig R, Driscoll M, Tang AS, Gao W, Runningdeer E, Arwady MA, Weinstein RA for the Centers for Disease Control and Prevention Epicenters Program. Electronic Public Health Registry of Extensively Drug-Resistant Organisms, Illinois, USA. Emerg Infect Dis. 2015 Oct;21(10):1725-32. doi: 10.3201/eid2110.150538.
• Haverkate MR, Bootsma CJ, Weiner S, Blom D, Lin MY, Lolans K, Moore N, Lyles RD, Weinstein RA, Bonten MJM, Hayden MK and for the CDC Prevention Epicenters Program. Modeling spread of KPC-producing bacteria in long-term acute care hospitals in the Chicago region, USA. Infect Control Hosp Epidemiol. 2015 Oct;36(10):1148-54.
• Logan LK, Renschler JP, Gandra S, Weinstein RA, Laxminarayan R for the CDC Epicenters Prevention Program. Carbapenem Resistant Enterobacteriaceae in Children, United States, 1999-2012. Emerg Infect Dis. 2015 Nov;21(11):2014-21. doi: 10.3201/eid2111.150548.

• Reddy SC, Valderrama AL, Kuhar DT. Improving the Use of Personal Protective Equipment: Applying Lessons Learned. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S165-S70.
• O’Hara LM, Calfee DP, Miller LG, et al. Optimizing Contact Precautions to Curb the Spread of Antibiotic-resistant Bacteria in Hospitals: A Multicenter Cohort Study to Identify Patient Characteristics and Healthcare Personnel Interactions Associated With Transmission of Methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S171-S7.
• Phan LT, Maita D, Moritz DC, et al. Environmental Contact and Self-contact Patterns of Healthcare Workers: Implications for Infection Prevention and Control. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S178-S84.
• Harrod M, Petersen L, Weston LE, et al. Understanding Workflow and Personal Protective Equipment Challenges Across Different Healthcare Personnel Roles. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S185-S91.
• Baloh J, Reisinger HS, Dukes K, et al. Healthcare Workers’ Strategies for Doffing Personal Protective Equipment. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S192-S8.
• Drews FA, Mulvey D, Stratford K, Samore MH, Mayer J. Evaluation of a Redesigned Personal Protective Equipment Gown. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S199-S205.
• Toth DJA, Khader K, Beams A, et al. Model-based Assessment of the Effect of Contact Precautions Applied to Surveillance-detected Carriers of Carbapenemase-producing Enterobacteriaceae in Long-term Acute Care Hospitals. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S206-S13.
• Mumma JM, Durso FT, Casanova LM, et al. Common Behaviors and Faults When Doffing Personal Protective Equipment for Patients With Serious Communicable Diseases. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S214-S20.
• Mumma JM, Durso FT, Erukunauakpor K, et al. Variability in the Duration and Thoroughness of Hand Hygiene. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S221-S3.
• Kpadeh-Rogers Z, Robinson GL, Alserehi H, et al. Effect of Glove Decontamination on Bacterial Contamination of Healthcare Personnel Hands. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S224-S7.
• Robinson GL, Hitchcock S, Kpadeh-Rogers Z, et al. Preventing Viral Contamination: Effects of Wipe and Spray-based Decontamination of Gloves and Gowns. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S228-S30.
• Therkorn J, Drewry D, Andonian J, et al. Development and Comparison of Complementary Methods to Study Potential Skin and Inhalational Exposure to Pathogens During Personal Protective Equipment Doffing. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S231-S40.
• Wong MF, Matić Z, Campiglia GC, et al. Design Strategies for Biocontainment Units to Reduce Risk During Doffing of High-level Personal Protective Equipment. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S241-S7.
• Andonian J, Kazi S, Therkorn J, et al. Effect of an Intervention Package and Teamwork Training to Prevent Healthcare Personnel Self-contamination During Personal Protective Equipment Doffing. Clin Infect Dis. 2019 Sep 13;69(Supplement_3): S248-S55.

ID Week 2014

October 8-12, 2014, in Philadelphia, PA. 

• Methicillin-Resistant Staphylococcus aureus (MRSA)
  • Hayden M, Lolans K, Haffenreffer K, Avery T, Kleinman K, Li H, Kaganov R, Lankiewicz J, Moody J, Septimus E, Weinstein R, Hickok J, Jernigan J, Perlin J, Huang S, Platt R Chlorhexidine (CHG) and mupirocin susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) isolates in the REDUCE MRSA trial
  • Cluzet VC, Gerber JS, Nachamkin I, Metlay J, Zaoutis T, Julian KG, Royer D, Linkin DR, Coffin SE, Margolis DJ, Hollander JE, Mistry RD, Gavin LJ, Tolomeo P, Wise JA, Wheeler MK, Bilker W, Han X, Hu B, Fishman NO, Lautenbach E and the CDC Prevention Epicenters Program. Duration of Colonization with Methicillin-resistant Staphylococcus aureus and Determinants of More Rapid Clearance of Colonization
  • Cluzet VC, Tolomeo P, Lautenbach E and The CDC Prevention Epicenters Program.
    Prevalence and Epidemiology of Mupirocin Resistance Among Those Colonized with Methicillin-resistant Staphylococcus aureus in the Community.
• Clostridium difficile Infection
  • Caroff DA, Edelstein PH, Hamilton K, Pegues DA
    The relationship of Bristol Stool Scale to Clostridium difficile infection
• Surgical Site Infections
  • Huang S, Septimus E, hayden M, Kleinman K, Sturtevant J, Avery T, Moody J, Hickok J, Lankiewicz J, Gombosev A, Kaganov R, Haffenreffer K, Jernigan J, Perlin J, Platt R, Weinstein R
    Impact of Body Surface Decolonization on Bacteriuria and Candiduria in a Cluster-Randomized Trial of Intensive Care Units
• Ventilator-associated Pneumonia
  • Klompas M, Anderson D, Trick W, Babcock H, Sinkowitz- Cochran R, Ely W, Jernigan J, Magill S, Lyles R, O’Neil C, Balas M, Murphy M, Cox C, Lautenbach E, Sexton D, Fraser V, Weinstein R, Platt R
    The Preventability of Ventilator-Associated Events: The CDC Prevention Epicenters’ Wake Up and Breathe Collaborative
• Blood Stream Infections
  • Hickok J, Moody J, Kleinman K, Avery T, Huang S, Bienvenu S, Perlin J, Platt R, Septimus E Rapid Dissemination of Universal Decolonization in Adult Intensive Care Units (ICUs) Reduces Healthcare-Associated (HA) Central Line Associated Bloodstream Infections (CLABSI) in over 100 Community Hospitals in a Single Healthcare System
• Technology, Surveillance, and Antimicrobial Stewardship
  • Baker M, Huang S, Letourneau A, Kaganov R, Peeples J, Drees M, Yokoe D, for the CDC Prevention Epicenters
    How Do Hospitals Detect Outbreaks?
  • Cluzet VC, Gerber JS, Nachamkin I, Metlay J, Zaoutis T, Julian KG, Royer D, Linkin DR, Coffin SE, Margolis DJ, Hollander JE, Mistry RD, Gavin LJ, Tolomeo P, Wise JA, Wheeler MK, Bilker W, Han X, Hu B, Fishman NO, Lautenbach E and the CDC Prevention Epicenters Program A Randomized Controlled Trial of the Effect of Total Household Decolonization on Termination of Colonization with Methicillin-Resistant Staphylococcus aureus
  • Schwartz DN, Cooke J, Peglow SR, Lyles R, Gueret R, Xamplas R, Singh K, Niklinski W, Cypser R, Fogg L, Weinstein RA, Balk R, and CDC Prevention Epicenters.
    Antibiotic Prescribing Adherence to Procalcitonin (PCT)-Generated Recommendations in Two Academic Medical Intensive Care Units (MICUs) (Abstract 176)

ID Week 2013

October 2-6, 2013, in San Francisco, California. 

• Methicillin-Resistant Staphylococcus aureus (MRSA)
  • Courtney A. Gidengil MD, MPH, Charlene Gay, BA, Grace Lee MD, MPH
    Cost-Effectiveness of Screening-Based Strategies to Prevent MRSA Transmission and Infection
  • LP Knelson, DA Williams, M Gergen, WA Rutala, DJ Weber, DJ Sexton, DJ Anderson, and the CDC Prevention Epicenter Program
    Environmental Contamination by Patients Infected or Colonized with MRSA or VRE: A multicenter study
• Multi-Drug Resistant Organisms
  • Michael Calderwood, MD MPH, Christopher A. Desjardins, PhD, George Sakoulas, MD, Robert Nicol, PhD, Andrea Dubois, Mary L. Delaney, PhD, Ken Kleinman, ScD, Lisa A. Cosimi, MD, Michael Feldgarden, PhD, Andrew B. Onderdonk, PhD, Bruce W. Birren, PhD, Richard Platt, MD MS, Susan S. Huang, MD, MPH
    Staphylococcal enterotoxin P predicts bacteremia in hospitalized patients colonized with methicillin-resistant Staphylococcus aureus
  • Mary K Hayden, MD, Michael Y. Lin, MD, MPH, Rosie D. Lyles-Banks, MD, MHA, Shayna Weiner, MPH, Nicholas Moore, MS, MLS (ASCP), Karen Lolans-Mazza, BS, Huiyuan Zhang, MS, Louis Fogg, PhD, Donald Blom, RN, BA, Caroline Thurlow, MD, Monica Sikka, MD, David W. Hines, MD, Robert A Weinstein, MD, for The CDC Prevention Epicenters Program
    Effect of a Bundled Intervention on Infection and Colonization due to Klebsiella pneumoniae Carbapenemase-Producing Enterobacteriaceae (KPC) at 4 Long-Term Acute Care Hospitals (LTACHs) in Chicago
  • Rosie D. Lyles-Banks, MD, MHA, Karen Lolans-Mazza, BS, Shayna Weiner, MPH, Donald Blom, RN, BA, Nicholas Moore, MS, MLS (ASCP), Michael Y. Lin, MD, MPH, Robert A Weinstein, MD, Mary K Hayden, MD, for the CDC Prevention Epicenter Program
    Healthcare Worker Hand Carriage of Klebsiella Pneumoniae Carbapenemase-Producing Enterobacteriaceae and other Gram Negative Rods at Long Term Acute Care Hospitals
  • Michael Y. Lin, MD, MPH, Donald Blom, RN, BA, Rosie D. Lyles-Banks, MD, MHA, Karen Lolans-Mazza, BS, Nicholas Moore, MS, MLS (ASCP), Shayna Weiner, MPH, Caroline J. Thurlow, MD, Monica K. Sikka, MD, David W. Hines, MD, Robert A Weinstein, MD, Mary K Hayden, MD, for the CDC Prevention Epicenter Program
    The effectiveness of routine daily chlorhexidine (CHG) bathing in reducing Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae (KPC) skin burden among long-term acute care hospital (LTACH) patients
• Surgical Site Infections
  • Meghan Baker, MD ScD, David Kaelber, MD PhD MPH, Megan Mazza, MPH, David Bar-Shain, MD, Bob Zambarano, PhD, Pedro Moro, MD,MPH, Richard Platt, MD MS and Michael Klompas, MD MPH
    Automated Detection and Reporting of Vaccine Adverse Events: ESP-VAERS
  • Michael Calderwood, MD MPH, Ken Kleinman, ScD, Claire Canning, MA, Julie Lankiewicz, MPH, Richard Platt, MD MS and Susan S. Huang, MD, MPH
    Improving Surveillance for Deep and Organ/Space Surgical Site Infections Following Coronary Artery Bypass Graft Surgery and Hip Arthroplasty
  • Michael Calderwood, MD MPH, Ken Kleinman, ScD, Dale W. Bratzler, DO, MPH, Rebecca E. Kaganov, BA, Christina B. Bruce, BA, Elizabeth C. Balaconis, BA, Claire Canning, MA, Richard Platt,
    Presentation Title: Medicare Claims Successfully Track Surgical Site Infections Following Vascular Surgery in U.S. Hospitals
  • Deborah Yokoe, MD MPH – MTP
    Changes in SSI Reporting in 2014 and 2015, Implications and Practice Change
• Ventilator Associated Events/ Ventilator Associated Complications
  • Michael Klompas, MD MPH
    Early Success and Challenges in Ventilator-Associated Event Reporting to NHSN
  • Sarah C. Lewis, MD, Lingling Li, PhD, Michael V. Murphy, BA, Michael Klompas, MD, MPH
    Presentation Title: Risk Factors for Ventilator-Associated Events: A Case-Control Multivariate Analysis
  • Maaike SM van Mourik, MD MSc, Michael V. Murphy, BA, Michael Klompas, MD MPH
    Risk-Adjustment for Ventilator-Associated Events Using Electronic Medical Record Data
• Technology and Surveillance
  • Louise Elaine Vaz, MD, Ashish Jha, MD, MPH, Alison Tse Kawai, ScD, SM, Robert Jin, MS, Michael S. Calderwood, MD, MPH, Grace M. Lee, MD, MPH
    Healthcare-associated infection rates in safety net and non-safety net hospitals 2006-2011
  • DJ Anderson, WA Rutala, LP Knelson, RW Moehring, LF Chen, DJ Weber, DJ Sexton, and the CDC Prevention Epicenter Program
    Inter-hospital Variation in Time Required for Hospital Room Ultraviolet (UV)-C Irradiation: Preliminary Experience from the Benefits of Enhanced Terminal Room (BETR) Disinfection Study
  • Sarah R. Peglow, MD, Rosie D. Lyles-Banks MD, MHA, Haris Khan, David N. Schwartz MD, for the CDC Prevention Epicenter Program.
    Biweekly Case Audit with Concurrent Intensivist Feedback to Improve Antimicrobial Use in a Medical Intensive Care Unit

ID Week 2012

October 16-21, 2012, in San Diego, California.

• Methicillin-Resistant Staphylococcus aureus (MRSA)
  • Rosie D. Lyles-Banks, MD, MS; Michael Y. Lin, MD, MPH, Karen Lolans, BS, Mary K. Hayden, MD, Hong Li, MS, Alexander J. Kallen, MD, MPH, Stephen G. Weber, MD, MS, Robert A. Weinstein, MD, William E. Trick, MD
    Methicillin-Resistant Staphylococcus Aureus (MRSA) Colonization among Neonatal and Pediatric Intensive Care Unit (ICU) Patients Following an Active Surveillance Mandate
  • Han, JH, Edelstein PH, Bilker WB, Lautenbach E
    The effect of staphylococcal cassette chromosome mec (SCCmec) type and clinical outcomes in methicillin-resistant Staphylococcus aureus bacteremia.
  • Han JH, Edelstein PH, Lautenbach E Reduced vancomycin susceptibility and staphylococcal cassette chromosome mec (SCCmec) type distribution in methicillin-resistant Staphylococcus aureus bacteremia
  • Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TA, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin J, Platt R for the CDC Prevention Epicenters and the AHRQ DEcIDE Network and Healthcare-Associated Infections Program
    Randomized Evaluation of Decolonization vs. Universal Clearance to Eliminate Methicillin-Resistant Staphylococcus aureus in ICUs (REDUCE MRSA Trial)
• Multi-Drug Resistant Organisms
  • Deverick Anderson, MD MPH, Maria F. Gergen, MT (ASCP), Emily Smathers, MPH, Daniel J. Sexton, MD, David J. Weber, MD, MPH, William A. Rutala, PhD, MPH and the CDC Prevention Epicenter Programs
    Effectiveness of Ultraviolet (UV)-C light against C. difficile, Acinetobacter, and Vancomycin-Resistant Enterococci in the Hospital Environment
  • Han JH, Nachamkin I, Tomoleo P, Bilker WB, Lautenbach E
    >Risk factors for efflux pump overexpression in fluoroquinolone-resistant Escherichia coli.
  • Chen, LF, Sexton,DJ, Anderson, DJ
    Widespread Dissemination of Group 1 CTX-M Genotype 15 Extended Spectrum Beta-Lactamase Producing Enterobacteriaceae among Patients Presenting to Community Hospitals – Clinical and Molecular Epidemiology.
  • Han JH, Kasahara K, Edelstein PH, Bilker WB, Lautenbach E
    Risk Factors for Infection or Colonization with CTX-M Extended-Spectrum Beta-Lactamase (ESBL)-Positive Escherichia coli
  • Datta R, Kleinman K, Rifas-Shiman S, Placzek H, Lankiewicz JD, Platt R, Huang SS
    Failure to Account for Treatment Indication Impacts Antimicrobial Predictors of Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant Enterococci (VRE) Acquisition
• Surgical Site Infections
  • Calderwood MS, Kleinman K, Bratzler DW, Ma A, Bruce CB, Kaganov RE, Canning C, Platt R, Huang SS.
    Using Medicare Claims to Identify U.S. Hospitals with a High Rate of Surgical Site Infection Following Hip Arthroplasty
  • Calderwood MS, Kleinman K, Tse A, Jin R, Platt R, Lee GM Examining the Impact of Medicare’s Policy of Non-Payment for Preventable Complications on Rates of Mediastinitis following Coronary Artery Bypass Graft
  • Alyssa R. Latourneau, Michael S. Calderwood, Susan S. Huang, Dale W. Bratzler, Allen Ma, Richard Platt, Deborah Yokoe for the CDC Prevention Epicenters
    Claims-Based Surveillance Improves Detection of Surgical Site infections Following Hysterectomy and Colorectal Surgery
  • Deborah S. Yokoe, Susan S. Huang, Julie Lankiewicz, Rebecca Kaganov, Christina Bruce, Sandra Berrios-Torres, and Richard Platt for the CDC Prevention Epicenters Program
    Managed Care Claims Data for Surgical Site Infection (SSI) Surveillance Following Ambulatory Surgery
• Ventilator Associated Pneumonia
  • Klompas M, Sinuff T, Jiang X, Day A, Muscedere J for the Canadian Critical Care Trials Group
    The Morbidity and Preventability of Ventilator- Associated Conditions Impact of National Policy on HAI Reporting and Prevention
• Blood Stream Infections
  • Faisal Alasmari, Nupur D. Kittur, Anthony J Russo, Kathleen M. McMullen, Kathleen Rensing, Erik R. Dubberke, Jennie L. Mayfield
    Impact of Alcohol Impregnated Protectors on Incidence of Catheter- Associated Blood Stream Infections
• Technology and Surveillance
  • Richard Platt MD, MS
    Rethinking the Approach to Case Findings and Study Surveillance Networks which Rely on Routinely Collected Electronic Health Information
  • Alsion Tse
    Comparing Billing vs. National Healthcare Safety Network Surveillance Rates of Hospital-Acquired Infections

• Rhee C, Murphy MV, Li L, Platt R, Klompas M; Centers for Disease Control and Prevention Epicenters Program. Improving documentation and coding for acute organ dysfunction biases estimates of changing sepsis severity and burden: a retrospective study. Crit Care. 2015 Sep 14;19(1):338.
• Rhee C, Murphy MV, Li L, Platt R, Klompas M; Centers for Disease Control and Prevention Prevention Epicenters Program. Lactate Testing in Suspected Sepsis: Trends and Predictors of Failure to Measure Levels. Crit Care Med. 2015 Aug;43(8):1669-76.
• Rhee C, Murphy MV, Li L, Platt R, Klompas M; Centers for Disease Control and Prevention Epicenters Program. Comparison of trends in sepsis incidence and coding using administrative claims versus objective clinical data. Clin Infect Dis. 2015 Jan 1;60(1):88-95.
• Han JH, Nachamkin I, Coffin SE, Gerber J, Garrigan C, Han X, Bilker WB, Wise J, Tolomeo P, Lautenbach E, for the Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program. Use of a combination biomarker algorithm to identify medical intensive care unit patients with suspected sepsis at very low likelihood of bacterial infection. Antimicrob Agents Chemother. 2015 Oct;59(10):6494-500. doi: 10.1128/AAC.00958-15. Epub 2015 Aug 3
• Gohil SK, Cao C, Phelan M, Tjoa T, Rhee C, Platt R, Huang SS; Centers for Disease Control and Prevention Epicenters Program. Impact of Policies on the Rise in Sepsis Incidence, 2000-2010. Clin Infect Dis. 2016 Mar 15;62(6):695-703. doi: 10.1093/cid/civ1019. Epub 2016 Jan 19.PMID:26787173

• Rhee C, Huang SS, Berríos-Torres SI, Kaganov R, Bruce C, Lankiewicz J, Platt R, Yokoe DS; Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program. Surgical site infection surveillance following ambulatory surgery. Infect Control Hosp Epidemiol. 2015 Feb;36(2):225-8.
• Calderwood MS, Kleinman K, Bratzler DW, Ma A, Kaganov RE, Bruce CB, Balaconis EC, Canning C, Platt R, Huang SS; CDC Prevention Epicenters Program; Oklahoma Foundation for Medical Quality. Medicare claims can be used to identify US hospitals with higher rates of surgical site infection following vascular surgery. Med Care. 2014 Oct;52(10):918-25.
• Calderwood MS, Kleinman K, Bratzler DW, Ma A, Bruce CB, Kaganov RE, Canning C, Platt R, Huang SS; Centers for Disease Control and Prevention Epicenters Program; Oklahoma Foundation for Medical Quality. Use of Medicare claims to identify US hospitals with a high rate of surgical site infection after hip arthroplasty. Infect Control Hosp Epidemiol. 2013 Jan;34(1):31-9.
• Yokoe DS, Khan Y, Olsen MA, Hooper DC, Greenbaum M, Vostok J, Lankiewicz J, Fraser VJ, Stevenson KB; Centers for Disease Control and Prevention Epicenters Program. Enhanced surgical site infection surveillance following hysterectomy, vascular, and colorectal surgery. Infect Control Hosp Epidemiol. 2012 Aug;33(8):768-73.
• Calderwood MS, Ma A, Khan YM, Olsen MA, Bratzler DW, Yokoe DS, Hooper DC, Stevenson K, Fraser VJ, Platt R, Huang SS; CDC Prevention Epicenters Program. Use of Medicare diagnosis and procedure codes to improve detection of surgical site infections following hip arthroplasty, knee arthroplasty, and vascular surgery. Infect Control Hosp Epidemiol. 2012 Jan;33(1):40-9.
• Bolon MK, Hooper D, Stevenson KB, Greenbaum M, Olsen MA, Herwaldt L, Noskin GA, Fraser VJ, Climo M, Khan Y, Vostok J, Yokoe DS; Centers for Disease Control and Prevention Epicenters Program. Improved surveillance for surgical site infections after orthopedic implantation procedures: extending applications for automated data. Clin Infect Dis. 2009 May 1;48(9):1223-9.
• Apisarnthanarak A, Jones M, Waterman BM, Carroll CM, Bernardi R, Fraser VJ (2003). Risk factors for spinal surgical site infections in a community hospital: A case-control study. Infection Control and Hospital Epidemiology, 24:31-6. DOI: 10.1086/502197
• Bolon M, Hooper D, Stevenson K, Greenbaum M, Olsen M, Platt R, Herwaldt L, Noskin G, Fraser V, Climo M, Khan Y, Vostok J, Yokoe D (2009). Improved Surveillance for Surgical Site Infection Following Orthopedic Implant Procedures: Extending Applications for Automated Data. Clinical Infectious Diseases, 48:1223-9.
• Hooper DC, Sands KE, Tully J, Herwaldt LA, Diekema DJ, Wong ES, Climo M, Platt R (2004). Enhanced identification of postoperative infections among inpatients. Emerging Infectious Diseases, 10:1924-1930.
• Olsen M, Higham-Kessler J, Yokoe D, Butler A, Stevenson K, Khan Y, Fraser V (2009). Developing a Risk Stratification Model for Surgical Site Infection after abdominal Hysterectomy. Infection Control and Hospital Epidemiology, 30:1077-83.
• Olsen MA, Butler AM, Willers DM, Devkota P, Gross GA, Fraser VJ (2008). Risk factors for surgical site infection following low transverse cesarean section. Infection Control and Hospital Epidemiology, 29(6):477-84.
• Olsen MA, Chu-Ongsakul S, Brandt KE, Dietz JR, Mayfield J, Fraser VF (2008). Hospital-associated costs due to surgical site infection after breast surgery. Archives of Surgery,143:53-60.
• Olsen MA, Krauss M, Agniel D, Schootman M, Gentry CN, Yan Y, Damiano RJ Jr., Fraser VJ (2008). Mortality associated with bloodstream infection following coronary artery bypass surgery. Clinical Infectious Diseases, 46:1537-46.
• Olsen MA, Nepple JJ, Riew KD, Lenke LG, Bridwell KH, Mayfield JL, Fraser VJ (2007). Risk factors for surgical site infection following orthopaedic spinal operations. The Journal of Bone and Joint Surgery, 90:62-69. DOI:10.2106/JBJS.F.01515.
• Yokoe DS, Noskin GA, Cunningham SM, Zuccotti G, Plaskett T, Fraser VJ, Olsen MA, Tokars N, Solomon S, Perl TM, Cosgrove SE, Tilson RS, Greenbaum M, Olsen MA, Lefta M, Dietz JR, Brandt KE, Aft R, Matthews R, Mayfield J, Fraser VF (2008). Risk factors for surgical site infection after major breast operation. Journal of the American College of Surgeons, 207:326-35.

• Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, Avery TR, Lankiewicz J, Gombosev A, Terpstra L, Hartford F, Hayden MK, Jernigan JA, Weinstein RA, Fraser VJ, Haffenreffer K, Cui E, Kaganov RE, Lolans K, Perlin JB, Platt R; CDC Prevention Epicenters Program; AHRQ DECIDE Network and Healthcare-Associated Infections Program. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med. 2013 Jun 13;368(24):2255-65.
• Bleasdale SC, Trick WE, Gonzalez IM, Lyles RD, Hayden MK, and Weinstein RA (2007). Effectiveness of chlorhexidine bathing to reduce catheter-associated bloodstream infections in medical intensive care unit patients. Archives of Internal Medicine, 167(19):2073-9.
• Climo MW, Septowitz KA, Zucotti G, Fraser VJ, Warren DK, Perl TM, Speck K, Jernigan JA, Robles JR, Wong ES (2009). The Effect of daily bathing with Chlorhexidine on the Acquisition of Methicillin-resistant Staphylococcus aureus, Vancomycin-resistant Enterococci and Healthcare-associated Bloodstream Infections: Results of a Quasi-experimental Multicenter Trial. Critical Care Medicine, 37(6):1858-65.
• Popovich K, Hota B, Hayes R, Weinstein R, Hayden M (2009). Effectiveness of routine Patient Cleansing with Chlorhexidine Gluconate for Infection Prevention in the Medical Intensive Care Unit. Infection Control and Hospital Epidemiology, 30(10):959-963.
• Huang SS, Septimus E, Hayden MK, Kleinman K, Sturtevant J, Avery TR, Moody J, Hickok J, Lankiewicz J, Gombosev A, Kaganov RE, Haffenreffer K, Jernigan JA, Perlin JB, Platt R, Weinstein RA; Agency for Healthcare Research and Quality (AHRQ) DEcIDE Network and Healthcare-Associated Infections Program, and the CDC Prevention Epicenters Program. Effect of body surface decolonisation on bacteriuria and candiduria in intensive care units: an analysis of a cluster-randomised trial. Lancet Infect Dis. 2016 Jan;16(1):70-9. doi: 10.1016/S1473-3099(15)00238-8. Epub 2015 Nov 27.
• Huang SS, Septimus E, Hayden MK, Kleinman K, Sturtevant J, Avery TR, Moody J, Hickok J, Lankiewicz J, Gombosev A, Kaganov RE, Haffenreffer K, Jernigan JA, Perlin JB, Platt R, Weinstein RA; Agency for Healthcare Research and Quality (AHRQ) DEcIDE Network and Healthcare-Associated Infections Program, and the CDC Prevention Epicenters. Effect of body surface decolonisation on bacteriuria and candiduria in intensive care units: an analysis of a cluster-randomised trial. Lancet Infect Dis. 2016 Jan;16(1):70-9. doi: 10.1016/S1473-3099(15)00238-8. Epub 2015 Nov 27.PMID:26631833

• Klompas M, Anderson D, Trick W, Babcock H, Kerlin MP, Li L, Sinkowitz-Cochran R, Ely EW, Jernigan J, Magill S, Lyles R, O’Neil C, Kitch BT, Arrington E, Balas MC, Kleinman K, Bruce C, Lankiewicz J, Murphy MV, E Cox C, Lautenbach E, Sexton D, Fraser V, Weinstein RA, Platt R; CDC Prevention Epicenters. The preventability of ventilator-associated events. The CDC Prevention Epicenters Wake Up and Breathe Collaborative. Am J Respir Crit Care Med. 2015 Feb 1;191(3):292-301.
• Lewis SC, Li L, Murphy MV, Klompas M; CDC Prevention Epicenters. Risk factors for ventilator-associated events: a case-control multivariable analysis. Crit Care Med. 2014 Aug;42(8):1839-48.
• Klompas M, Magill S, Robicsek A, Strymish JM, Kleinman K, Evans RS, Lloyd JF, Khan Y, Yokoe DS, Stevenson K, Samore M, Platt R; CDC Prevention Epicenters Program. Objective surveillance definitions for ventilator-associated pneumonia. Crit Care Med. 2012 Dec;40(12):3154-61.
• Klompas M, Kleinman K, Khan Y, Evans RS, Lloyd JF, Stevenson K, Samore M, Platt R; CDC Prevention Epicenters Program. Rapid and reproducible surveillance for ventilator-associated pneumonia. Clin Infect Dis. 2012 Feb 1;54(3):370-7.
• Klompas M, Khan Y, Kleinman K, Evans RS, Lloyd JF, Stevenson K, Samore M, Platt R; CDC Prevention Epicenters Program. Multicenter evaluation of a novel surveillance paradigm for complications of mechanical ventilation. PLoS One. 2011 Mar 22;6(3):e18062.
• Klompas M, Kleinman K, Platt R (2008). Development of an Algorithm for Surveillance of Ventilator-associated Pneumonia With Electronic Data and Comparison of Algorithm Results With Clinician Diagnoses. Infection Control and Hospital Epidemiology, 29(1):31-7.
• Cocoros N, Kleinman K, Priebe GP, Gray JE, Logan LK, Larsen G…and Lee, GM on behalf of the PVAC Study Team. Ventilator Associated Events in Neonates and Children—A New Paradigm. Crit Care Med. 2016 Jan;44(1):14-22.
• Klompas M, Li L, Szumita P, Kleinman K, Murphy MV. CDC Prevention Epicenters Program. Associations between different sedatives and ventilator-associated events, length-of-stay, and mortality in mechanically ventilated patients. Chest. 2015 Oct22.doi: 10.1378/chest.15-1389.