Prevention Guidelines

2019 Guidelines Update

All group B Streptococcus (GBS) prevention guidance found on CDC’s website pertains to the 2010 guidelines only. CDC will maintain these resources until the American Academy of Pediatrics (AAP), American College of Obstetricians and Gynecologists (ACOG), and American Society of Microbiology (ASM) publish all their updated guidance.

2019 ACOG Committee Opinion and AAP Clinical Report

In June 2019, ACOG published a new Committee Opinion—Prevention of Group B Streptococcal Early-Onset Disease in Newbornsexternal icon—which all obstetric care providers should now be following. ACOG’s guidance replaces the 2010 guidelines published by CDC.

In July 2019, AAP published a new clinical report—Management of Infants at Risk for Group B Streptococcal Diseaseexternal icon—which all neonatal providers should now be following. AAP’s Clinical Report replaces the 2010 guidelines published by CDC. Additionally, in late 2018, AAP released guidance that pertains to management of infants with suspected or proven early-onset sepsisexternal icon.

ASM is currently reviewing GBS laboratory guidance. In the meantime, microbiologists should continue to follow the guidance included in the 2010 GBS guidelines. Once all three organizations finish publishing updated GBS prevention guidance, CDC will remove all guidelines resources from its website.

CDC, AAP, ACOG, ASM, the American College of Nurse-Midwives, and the American Academy of Family Physicians have worked together on GBS prevention for many years and new guidance represents both progress and continued collaboration between these groups. These organizations remain committed to working together to protect newborns from GBS. CDC will continue to stay engaged actively in evaluating guidelines implementation along with impact and trends in disease burden. CDC will also continue to build the evidence base relevant to maternal GBS vaccination.

2010 Guidelines for the Prevention of Perinatal Group B Streptococcal Disease

HTML | PDF pdf icon[1.54 MB, 36 pages]

CDC published guidelines for the prevention of perinatal GBS disease in the Morbidity and Mortality Weekly Report (MMWR) on November 19, 2010. These 2010 guidelines were developed using an evidence-based approach in collaboration with several professional associations. They received formal endorsements from: