CDC Streptococcus Laboratory
CDC’s Streptococcus Laboratory provides support for active population-based surveillance for invasive streptococcal disease, primarily caused by groups A and B streptococci and Streptococcus pneumoniae. It supports state and local health departments in the United States to characterize streptococcal isolates and is active in many international collaborations. The laboratory is a reference center for the identification and characterization of streptococci and other Gram-positive catalase-negative cocci.
M protein gene (emm) typing, databases, resources, and protocols...
MICs predicted by penicillin binding protein gene types, resources, protocols, and the global pneumococcal strain bank...
PCR serotyping methods and resources...
Methods for identifying other species and types of streptococci, including PCR assays...
Frequently asked questions about the Streptococcus Laboratory’s reference services and request forms...
Papers published by the Streptococcus Laboratory...
Opportunities concerning molecular epidemiology and biology at the Streptococcus Laboratory...
Group A streptococci: Submit emm gene sequence to determine emm subtype of your strain.
There are many species and subspecies within the Streptococcus genus. CDC provides protocols for how to identify and differentiate species of streptococci.
- CDC Streptococcus Laboratory GAS Bioinformatic Pipelines for S. agalactiae, S. pyogenes, and S. pneumoniaeExternal
Sequences and pipelines related to the three principal streptococcal pathogens… - Emerging Infections Program/Active Bacterial Core surveillance (ABCs)
Information about ABCs, the source of many of the CDC Streptococcus Laboratory’s group A streptococcal isolates - Rockefeller University’s Laboratory of Bacterial Pathogenesis and ImmunologyExternal
Information about group A streptococci and Dr. Lancefield’s strains… - Nizet LabExternal
Information about group A streptococci and other hemolytic streptococci… - Multilocus Sequence Typing DatabasesExternal
MLST databases for group A streptococci, group B streptococci, pneumococci, and other bacterial pathogens… - Pneumococcal Molecular Epidemiology NetworkExternal
Information about global surveillance of antibiotic resistant S. pneumoniae… - Global Pneumococcal Sequencing (GPS) Project External
A worldwide genomic survey of the impact of vaccination on S. pneumoniae… - Group A Streptococcal Disease
Information about group A streptococcal disease… - Group B Streptococcal Disease
Information about group B streptococcal disease… - Pneumococcal Disease
Information about pneumococcal disease…