HPV-Associated Cancer Rates by State

In the following map, the states are divided into groups based on the rates at which people were diagnosed with an HPV-associated cancer during 2011–2015. The rates are the average numbers out of 100,000 people who developed cancer each year.*

*Note: This study used cancer registry data to estimate the amount of HPV-associated cancer in the United States by examining cancer in parts of the body and cancer cell types that are more likely to be caused by HPV. Cancer registries do not collect data on the presence or absence of HPV in cancer tissue at the time of diagnosis. In general, HPV is thought to be responsible for about 91% of cervical cancers, 75% of vaginal cancers, 69% of vulvar cancers, 63% of penile cancers, 91% of anal cancers, and 70% of oropharyngeal cancers.

Rates are per 100,000 and age-adjusted to the 2000 U.S. Standard Population (19 age groups — Census P25-1130) standard.

Data are from population-based cancer registries participating in CDC’s National Program of Cancer Registries (NPCR) and/or the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program for 2011 to 2015, covering 100% of the U.S. population.

HPV-associated cancers were defined as cancers at specific anatomic sites with specific cellular types in which HPV DNA frequently is found. All cancers were confirmed histologically. Cervical cancers (ICD-O-3 site codes C53.0–C53.9) are limited to carcinomas (ICD-O-3 histology codes 8010–8671, 8940–8941). Vaginal (ICD-O-3 site code C52.9), vulvar (ICD-O-3 site codes C51.0–C51.9), penile (ICD-O-3 site codes C60.0–60.9), anal (ICD-O-3 site code C21.0–C21.9), rectal (ICD-O-3 site code C20.9) and oropharyngeal (ICD-O-3 site codes C01.9, C02.4, C02.8, C05.1, C05.2, C09.0, C09.1, C09.8, C09.9, C10.0, C10.1, C10.2, C10.3, C10.4, C10.8, C10.9, C14.0, C14.2 and C14.8) cancer sites are limited to squamous cell carcinomas (ICD-O-3 histology codes 8050–8084, 8120–8131).


Data source: National Program of Cancer Registries SEER*Stat Database: U.S. Cancer Statistics Incidence Analytic file 1998–2015. United States Department of Health and Human Services, Centers for Disease Control and Prevention. Released June 2018, based on the November 2017 submission.

Viens LJ, Henley SJ, Watson M, Markowitz LE, Thomas CC, Thompson TD, Razzaghi H, Saraiya M, Centers for Disease Control and Prevention (CDC). Human papillomavirus–associated cancers—United States, 2008–2012. MMWR 2016;65(26):661–666.

Page last reviewed: August 20, 2018