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Vaccine Safety Datalink Data Sharing Program at NCHS Research Data Center

The Vaccine Safety Datalink project (VSD) is a collaborative project between the CDC and several health plans.  Established in 1990, this project collects utilized health data from participating health plans in order to monitor and evaluate the safety of vaccines.  More information on the VSD can be found:

Access to VSD data at the RDC

VSD data created before 2000 and datasets from studies published after 2002, can be accessed at CDC’s Research Data Center (RDC), housed within the National Center for Health Statistics (NCHS), allows researchers to analyze restricted data in a secure environment. The remote access system at RDC provides a way for analysis that protects the privacy and confidentiality of the data collected, as required under the Assurance of Confidentiality.

The NCHS RDC has created VSD data sharing guidelines to assist interested researchers access VSD data. 


Data and Documentation:

For new vaccine safety studies using data prior to 2000, the VSD Data Dictionary should be utilized to determine variables needed.

2000 Vaccine Safety DataLink Data Dictionary [PDF - 645 KB]

The VSD Data Dictionary includes:

For re-analyses of published studies, please request data dictionary for the specific study of interest from the Research Data Center at

Approved Projects – Next Steps

Following receipt of IRB approvals, RDC will arrange for access to data following the general data sharing processes as described in Step 5:  Approved Projects:  Next Steps

Always discuss next steps with your RDC Analyst.

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