Clinical Immunization Safety Assessment (CISA) Project Current Studies
CISA studies use the most current methods and technology to investigate questions of key importance to vaccine safety.
Studies initiated under the CISA Project from 2012 to the present.
- Assessing Fever Rates in Children ages 24 to 59 months after Live Attenuated Influenza Vaccine(LAIV) or Inactivated Influenza Vaccines (IIV) Using Text Messaging for U.S. influenza vaccines in 2012–13& 2013-2014
Some children have fevers after receiving some vaccines. This study is assessing the rates of fever in healthy 24-59 month old children receiving live attenuated influenza vaccine (LAIV) compared to those receiving Inactivated Influenza Vaccines (IIV). More information, see about this study can be found at ClinicalTrials.gov
Lead CISA Site: Columbia University.
- Pilot Study to Assess Flares Following Inactivated Influenza Vaccine in Children with Systemic Lupus Erythematosus (SLE)
Vaccines stimulate the immune system to develop protection against diseases. The effect of vaccination on disease progression among people with autoimmune diseases who are immunosuppressed is not well studied. CISA is conducting a pilot study of inactivated influenza vaccine (IIV) safety in children/adolescents with systemic lupus erythematosus (SLE) who are immunosuppressed, in order to inform methods for a larger study assessing association of IIV and SLE flares.
Lead CISA Site: Vanderbilt University, with subcontract to the Baylor Institute for Immunology Research (BIIR).