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IIS Sentinel Site Profiles

IIS chosen as Sentinel Sites have been state or large urban systems. There are two types of sentinel sites: capacity-building and implementation sites. All sites primarily work to meet data quality Registry/IIS Certification Standards and provide support for routine analysis of IIS data. Sites receiving funds collect timely and complete immunization histories in a specific geographic area of contiguous zip codes or census tracts that are usually subsets of the statewide IIS database.

See Q&A About Sentinel Sites for additional details.

Profiles of Current Sentinel Sites (2008-2012)

Capacity-building Sites

Implementation Sites


Examples of Sentinel Site Work

  1. Uptake of 13-Valent Pneumococcal Conjugate Vaccine (PCV13) among children aged 0 to 59 months — Select U.S. Regions, 2010-1011. MMWR 2011; 60 (43): 1477-1481.
  2. Up-to-date Haemophilus influenzae type b vaccination coverage during a vaccine shortage. [8 pages] Pediatrics 2011;127:e707-12.
  3. Assessing the Relationship Between Seasonal and H1N1 Influenza Vaccination Status in Michigan Children, 2009-2010. Public Health Rep 2011;126 Suppl 2:70-77.
  4. Using the North Dakota Immunization Information System (NDIIS) to determine adolescent vaccination rates and uptake. Public Health Rep 2011; 126 Suppl 2:78-86.
  5. The Effect of Policy Changes on Hepatitis A Vaccine Uptake in Arizona Children, 1995-2008. Public Health Rep 2011;126 Suppl 2:87-96.
  6. Leveraging state immunization information systems to measure the effectiveness of rotavirus vaccine. [10 pages] Pediatrics 2011;128(6):e1-8.
  7. Influenza vaccination coverage among children aged 6 months - 18 years — Eight Immunization Information System Sentinel Sites, United States, 2009-10 influenza season. MMWR 2010;59 (39):1266-9.
  8. A vaccination coverage among US children aged 12- 23 months — Immunization Information System Sentinel Sites, 2006-2009. MMWR 2010;59: (25): 76-9.
  9. Rotavirus vaccination coverage among infants aged 5 months — Immunization Information System Sentinel Sites, United States, June 2006-June 2009. MMWR 2010;59 (17): 521-4.

For more information on the IIS Sentinel Sites Project, contact Karen Cullen at

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