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TB Notes Newsletter

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No. 4, 2013

TB EPIDEMIOLOGIC STUDIES CONSORTIUM UPDATES

4th Semiannual Meeting of the Tuberculosis Epidemiologic Studies Consortium-II

Approximately 60 principal investigators, project coordinators, and other consortium personnel attended the 4th Semiannual Tuberculosis Epidemiologic Studies Consortium-II (TBESC-II) Meeting on September 12, 2013, at the Crowne Plaza Ravinia Hotel in Atlanta, GA. After a warm welcome by Dr. Phil LoBue, DTBE’s Acting Director, Dr. Denise Garrett presented the preliminary results of the Consortium’s main study, Task Order (TO) 1: Prospective Comparison of the Tuberculin Skin Test and Interferon-Gamma Release Assays in Diagnosing Infection with Mycobacterium tuberculosis and in Predicting Progression to Tuberculosis. Then, during a session moderated by Dr. Tom Navin, meeting participants discussed the input from TBESC-II’s Board of Advisors and the future directions for the Consortium. This discussion reflected the recognition that some adjustments need to be made, including potential changes in TO1 endpoints, intervention studies for improving latent TB infection (LTBI) diagnosis, and other next steps, including the creation of a “Protocol Revision Team.”

Other highlights from the meeting included updates from the Cost-effectiveness Working Group by Dr. Lisa Pascopella and from the Biobanking Working Group by Dr. Bob Belknap. There was also discussion on the Registry Match and repeat testing of IGRAs. Planning for the next TBESC meeting, which will be held in July 2014, is underway.

 

—Reported by Denise Garrett, MD
Div of TB Elimination

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