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Syphilis can have very serious consequences when left untreated.

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Fact Sheet

You should get tested regularly if you are pregnant, are a man who has sex with men, have HIV infection, and/or have partner(s) who have tested positive for syphilis.

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MSM Fact Sheet

75% of reported primary and secondary (P&S) syphilis cases are among men who have sex with men (MSM).

pregnant woman and her husband talking to doctor


Syphilis is easy to cure in its early stages. Pregnant women should be tested regularly for syphilis because infection with syphilis can cause serious problems in a baby.


Syphilis Profiles 2013 (February 9, 2015)

STD Surveillance Case Definitions - Includes updated definitions for Congenital Syphilis effective January 1, 2015 (December 3, 2014)

Primary and Secondary Syphilis — United States, 2005–2013 - MMWR May 9, 2014

STD Surveillance Case Definitions - Includes updated definitions for Gonorrhea and Syphilis effective January 1, 2014 (December 10, 2013)

Updated Syphilis Clinical Training (August 30, 2013)

Doxycycline and Tetracycline Shortage Update (March 1, 2013)

Incidence, Prevalence, and Cost of Sexually Transmitted Infections in the United States (February 13, 2013)