Abstract for Vendor Talk 1.2

 

 

The Importance of Using Relevant Testing Models for Testing of Wash-off Products

Presenter:
J. Hyldgaard for PLUM A/S, Denmark
Co-authors:
L. Halkier-Sørensenk, Skanderborg, Denmark
A. Severin Jensen, PLUM A/S, Assens, Denmark

Background

Wet Work is the most important cause for irritant contact dermatitis.

Frequent and/or long term use of tensides in different combinations is probably the most important factor in this process - in combination with water.

Therefore the use of relevant models for testing of tenside combinations is of utmost importance in order to have results that are transferable to the real life situation.

Objective

To develop a relevant method for testing the effect of wash products on the skin.

Methods

Practical studies of skin irritancy from wash products* under practical conditions of wet work.

Tests of the same wash products* in occlusive models.

Development of a new test method based on experience with wash products and skin in real life situations.

Test of the same products* in the new model.

Use of different data sampling models: Questionnaires, visual skin evaluation and TEWL. Comparing results from these models.

Results

Presentation of results from the studies demonstrates that results from the occlusive models do not correlate with real life experience.

Results from the newly developed model correlates with real life experience.

Conclusions

Testing of wash off products should be performed in a relevant wet model, where the wet conditions will be similar to real life wet work conditions.

For future development of irritancy testing models for wash products, it should be a premise that results from the model should correlate well with real life experience in wet work conditions of use.

 

Products*: Two different wash products based on combinations of syndets and on soaps.

 

Content last modified: 30 May 2005

 

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