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Proceedings of the International Conference on
Occupational & Environmental Exposures of Skin to Chemicals:
Science & Policy
Hilton Crystal City     September 8-11, 2002
 

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Factors Influencing Percutaneous Penetration in the Workplace and General Environment

Howard Maibach, MD, Prof, Derm, Department of Dermatology, University of California at San Francisco, San Francisco, CA, USA (Corresponding Author)

This presentation will provide the limited in vivo human and rhesus monkey flux data that permit realistic assessment of systemic dosing in man.

Factors for which data exist include: regional variation (~ 50 x factor from least to most permeable areas), effect of clothing, washing, soil, mass / unit area, and "delivery" vehicle (matrix).

Areas requiring further definition will be summarized.

 

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