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| September
8, 2002 |
| 12:30 PM –
5:00 PM |
Registration |
| 1:30 PM –
2:00 PM |
Opening Session, including
Welcome by Dr. Kathleen Rest, Deputy Director of NIOSH |
| 2:00 PM –
5:30 PM |
Session 1 – Defining
The Problem. |
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Dermal exposure was framed
within the context of both occupational and environmental scenarios.
Overviews of the conceptual frameworks for dermal exposures and
the range of toxic effects led into descriptions of the clinical
burden and management of dermatitis.
Session Chair: Päivikki
Susitaival
Plenary Titles and
Speakers:
2:00 PM
The Role of Exposure in the Chain of Events from Sources to Health
Outcomes: Dermal and Aggregate Exposures, Matti Jantunen, PhD,
KTL (National Public Health Institute), Kuopio, Finland (Abstract)
2:30 PM
Systemic Toxicity from Skin Exposures, James N. McDougal, PhD,
Wright State University School of Medicine, Dayton, Ohio, USA
(Abstract)
3:00 PM
Allergic Contact Dermatitis (ACD): Physiology and Pathology,
David Basketter, DSc, MRCPath, FIBiol, Unilever Colworth Laboratory,
Sharnbrook, Bedford, UK (Abstract)
3:30 PM Break
4:00 PM
Risk of Work-Related Dermatitis: Agents, Occupations and Host Factors,
Päivikki Susitaival, MD, PhD, North Karelia Central Hospital Dermatology
Department, Joensuu, Finland (Abstract)
4:30 PM
Diagnosis and Management of Occupational Skin Disease, James
S. Taylor, MD, Cleveland Clinic, Cleveland, Ohio, USA (Abstract)
5:00 PM Introduction
of Posters
Session Planning Committee:
Päivikki Susitaival, Coordinator
Elaine Cohen-Hubal
Boris Lushniak
James Taylor
|
| 2:00 PM –
8:30 PM |
Posters
and vendor exhibits |
| 6:30 PM –
8:30 PM |
Reception |
| |
|
| September
9, 2002 |
| 8:00 AM –
5:00 PM |
Registration |
| 8:00 AM –
6:00 PM |
vendor
exhibits |
| 8:30 AM –
12:00 PM |
Session 2 – Health
Effects And Hazard Identification |
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Chemicals on the skin
surface may penetrate the stratum corneum to reach viable tissue
and then be absorbed by the blood. Such uptake can lead to health
effects at the contact site and throughout the body. The talks in
this session focused on several aspects of this process, including
penetration, absorption, distribution and scientific approaches
for associating risk with chemicals when exposure occurs by the
dermal route.
Session Chairs: Pietro
Sartorelli and Frank Gerberick
Plenary Titles and
Speakers:
8:30 AM
Percutaneous Penetration Studies for Risk Assessment, Faith
Williams, PhD, The Medical School, University of Newcastle upon
Tyne, Newcastle upon Tyne, UK (Abstract)
9:00 AM
Factors Influencing Percutaneous Penetration in the Workplace and
General Environment, Howard Maibach, MD, Prof, Derm, University
of California at San Francisco, San Francisco, California, USA (Abstract)
9:30 AM
Theoretical Models of Percutaneous Absorption, John Corish,
BSc, MA, PhD and Dara Fitzpatrick, BSc, PhD, University of Dublin,
Dublin, Ireland (Abstract)
10:00 AM Break
10:30 AM
The Importance of Exposure and Potency in the Assessment of Skin
Sensitization Risk, Frank Gerberick, PhD, Procter and Gamble
Co., Cincinnati, Ohio, USA (Abstract)
11:00 AM
Criteria for Skin Notation in an International Perspective,
Jesper Bo Nielsen, PhD and Philippe Grandjean, MD, Institute of
Public Health, University of Southern Denmark, Odense, Denmark (Abstract)
11:30 AM Introduction
of Posters
Session Planning Committee:
Pietro Sartorelli, Coordinator
Heinz Ahlers
Peter Elsner
Pat Engasser
Frank Gerberick
Gerald Kennedy
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| September
9, 2002 |
| 2:00 PM –
5:30 PM |
Session 3 – Measuring
And Predicting Exposures |
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This session included
discussion of multiple aspects of dermal exposure assessment, including
current issues concerning measurement and assessment of dermal exposures
and the state of knowledge of the relation between metrics, measurement
techniques, and models. Exposures to different elements, i.e., fluids
(liquids, vapors), particles (soils, dusts, powders), and surface
residues were aspects of all the presentations.
Session Chair: Leena
Nylander-French
Plenary Titles and
Speakers:
2:00 PM
Dermal Exposure Processes and Mechanisms: Implications for Exposure
Sampling Methodology and Strategy, Derk Brouwer, PhD, TNO Chemistry,
Zeist, The Netherlands (Abstract)
2:35 PM
Issues in Understanding Dermal Exposures Resulting from Contact
with Contaminated Surfaces, Measuring Surface Contamination, and
Characterizing Transfers, Elaine A. Cohen-Hubal, PhD, US Environmental
Protection Agency, Research Triangle Park, North Carolina, USA (Abstract)
3:10 PM Introduction
of Posters
3:30 PM Break
4:00 PM
Measuring Dermal Exposure: Practical and Scientific Considerations,
Alastair Robertson, BSc (Hons), PhD, Institute of Occupational Medicine,
Edinburgh, UK (Abstract)
4:35 PM
Predictive Models of Dermal Exposure, John Kissel, PhD, PE,
University of Washington, Seattle, Washington, USA (Abstract)
5:10 PM Introduction
of Posters
Session Planning Committee:
Leena Nylander-French, Coordinator
Mark Boeniger
Bob Curtis
Elaine Cohen-Hubal
Richard Fenske
Hans Marquart
James N. McDougal
|
| 8:00 PM –
9:00 PM |
Planning for the Next
Conference - Open Meeting |
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|
| September
10, 2002 |
| 8:00 AM –
4:00 PM |
vendor
exhibits |
| 8:30 AM –
12:00 PM |
Session 4 – Controlling
Exposures And Prevention |
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Prevention of skin exposures
is the key to avoiding allergic and irritant contact dermatitis
and absorption of toxic chemicals through the skin. Selection of
evidenced-based interventions that are effective in preventing skin
exposures or a resulting illness were the focus of this session.
Whether or not control and prevention are successful has to be studied
by proper methods, so the session started with the design of research
to study the effectiveness of interventions. Methods of prevention
and control range from technical solutions through interventions
on behavior to personal protection. These aspects were a part of
the final group of talks.
Session Chair: Hans
Marquart
Plenary Titles and
Speakers:
8:30 AM
Intervention Research, Linda Goldenhar, MS, PhD, University
of Cincinnati, Cincinnati, Ohio, USA (Abstract)
9:05 AM
Work Practices and Behavioral Modifications - Evidence-Based Prevention
Programs and Implementation at Workplaces, Mari-Ann Flyvholm,
MSc, PhD, Lone Borg, MSc, PhD and Karen Mygind, MSc Pharm, National
Institute of Occupational Health, Copenhagen, Denmark (Abstract)
9:40 AM
Introduction of Posters
10:00 AM Break
10:30 AM
Practical and Cost-Effective Methods for Dermal Exposure Risk Management,
Chris Packham, Enviroderm Services, Evesham, UK (Abstract)
11:05 AM
Selection, Testing, and Effectiveness in the Field of PPE and Gloves,
Reinhard Oppl, MSc, Eurofins GfA (formerly MILJO-CHEMIE), Hamburg,
Germany (Abstract)
11:40 AM Introduction
of Posters
Session Planning Committee:
Hans Marquart, Coordinator
Ernie Braue
Mark Boeniger
Mari-Ann Flyvholm
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|
| September
10, 2002 |
| 2:00 PM –
5:30 PM |
Session 5 – Developing
Policy and Communicating Effectively |
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The goal of this session
was to explore the adequacy of government efforts to formulate policies
to address chemical exposures of the skin and the mechanisms employed
to communicate them to stakeholders and the general public. Presentations
described national and international efforts underway in this area,
their anticipated benefits, and the approaches being utilized to
implement them. A key feature of this session was to comment on
the effectiveness of these programs and to identify where improvements
might be made. Presentations from representatives of the regulated
community were included to illustrate their experiences and perspectives
on this issue.
Session Chair: Michael
Dellarco
Plenary Titles and
Speakers:
2:00 PM US
EPA's Recently Released Superfund Dermal Risk Assessment Guidance:
Application and Policy, Daniel Stralka, PhD, US Environmental
Protection Agency, San Francisco, California, USA (Abstract)
2:30 PM Protecting
Workers from Dermal Exposure - the German Experience, Eva Lechtenberg-Auffarth,
PhD and Bruno Orthen, PhD, Federal Institute for Occupational Safety
and Health (BAuA), Dortmund, Germany (Abstract)
3:00 PM Protecting
Workers from Dermal Exposure - The American Experience, Lyn
Penniman, MPH, US Occupational Safety and Health Administration,
Washington, DC, USA (Abstract)
3:30 PM Break
4:00 PM How
the Food Quality Protection Act Affects EPA Regulation of Pesticides
via the Dermal Route of Exposure, Elizabeth Doyle, PhD, US Environmental
Protection Agency, Washington, DC, USA (Abstract)
4:30 PM Prevention
of Contact Dermatitis by European Legislation, Carola Lidén,
MD, PhD, Dept Occupational and Environmental Dermatology, Stockholm
County Council; Karolinska Institutet, Stockholm, Sweden (Abstract)
5:00 PM Perspectives
on Industry Reactions to US Government Policies, Christine Chaisson,
PhD, Chaisson Scientific Advisors, Annandale, Virginia, USA (Abstract)
Posters
Session Planning Committee:
Mike Dellarco, Coordinator
Heinz Ahlers
Lisa Brosseau
Howard Maibach
John McAlinden
Lyn Penniman
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|
| September
11, 2002 |
| 8:30 AM –
3:00 PM |
Five Workshop Breakout
Sessions |
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Five Concurrent Workshop
Sessions covered the same general areas as the five Plenary Sessions:
1) Defining the Problem,
Discussion Leader – Boris Lushniak
2) Health Effects
and Hazard Identification, Discussion Leader – Frank Gerberick
3) Measuring and Predicting
Exposures, Discussion Leader – Elaine Cohen-Hubal
4) Controlling Exposures
and Prevention, Discussion Leaders – Mark Boeniger and Mari-Ann
Flyvholm
5) Developing Policy
and Communicating Effectively, Discussion Leader – John McAlinden
The Workshop discussions
focused on specific research and public health opportunities for
decreasing the burden of skin exposures to chemicals in both workplaces
and the general environment. What are some of the steps that could
be taken now or in the near future by researchers, teachers, occupational
hygienists, physicians, employers, workers, site managers and others
to effectively anticipate, identify, evaluate and control potentially
harmful exposures to chemicals by the dermal route? Questions that
each Workshop Session Leader could choose to consider during the
discussion were included in the Workshop
Discussion Paper (Version of 20 August).
Agenda for each Workshop
Session:
8:30 AM Workshop
Sessions convene
10:00 AM Break
10:30 AM Workshop
Sessions reconvene
12:00 PM Lunch
1:30 PM Workshop
Sessions reconvene
3:00 PM Break
|
| 3:30 PM -
4:30 PM |
Workshop Closing Session |
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Session Chair
– Sidney Soderholm
Each Workshop Session
discussion leader or a designee provided a brief overview of their
session and highlights of the discussion, focusing on next steps
that could be taken effectively to reduce the burden of dermal exposures
to chemicals. See the Workshop Discussion
Paper and the Proceedings for more
information. A product of the Workshops will be a document that
evolved from the Workshop Discussion Paper based on input of participants.
It is still being drafted.
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