Clinical trends in diagnosis and treatment of skin disorders caused by occupational or environmental exposures – allergic skin disorders
James S. Taylor MD
Cleveland Clinic Foundation, USA
Clinical Trends in Diagnosis
- Major occupational contact allergens and occupations
- Some chemicals cause both Type I (urticaria and asthma, etc) and Type IV reactions
- Patch testing is the major diagnostic tool: role of standard, and occupational trays plus patient’s own work materials
- Role of other diagnostic methods, including RAST and prick testing
- Measurement of occupational exposure to chemicals
- Role of other professions in diagnosis: industrial hygienists, chemists, occupational health physicians and nurses, and safety officers
- Information resources, including internet and MSDS’s
- Impediments to accurate diagnosis and treatment, including changes in manufacturers
Clinical Trends in Treatment
- Limitation of cutaneous exposure including European legislation and regulation
- Allergen alternatives including latex and rubber glove allergy
- Role of calcineurin inhibitors in the treatment of contact allergy, including alcohol intolerance and recent FDA warnings on use
- Role of other therapies including bath PUVA and systemic retinoids
Content last modified: 14 May 2005
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