NORA Manufacturing Sector Strategic Goals
927ZGNX - Quality Assurance Techniques for Laboratory Liquid AerosolsStart Date: 10/1/2008
End Date: 9/30/2011
Principal Investigator (PI)Name: Robert Glaser
Funded By: NIOSH
Primary Goal Addressed5.0
Secondary Goal Addressed6.0
Attributed to Manufacturing75%
This project addresses the goals of reducing respiratory disease primarily in the manufacturing sector. More accurate estimates of exposure dosage are needed to protect an estimated 2 million US workers exposed to MWF from occupational asthma, hyper-sensitivity pneumonitis, and possibly cancer. Such dosages are routinely underestimated due to significant evaporation of condensed aerosol and/or loss of vapor phase components of a MWF sample using filter-only sampling or during storage and shipment of samples. A novel device that uses a filter to sample the MWF aerosol components and a high-capacity low pressure drop sorbent bed to sample all volatile contaminants has been designed. Performance tests of this sampler for analysis of liquid aerosols with partner laboratories will assure the public that NIOSH meets the quality and transparency criteria of the 2001 Data Quality Act.
There are approximately 2 million workers in the United States exposed to MWF; such exposures can result in occupational asthma, hypersensitivity pneumonitis and possibly cancer. Current sampling and analytical techniques underestimate or ignore the nonvolatile and volatile MWF aerosol components and vapor-phase contaminants of the work environment. In order to truly estimate worker dosage due to inhaled MWF, a robust technique is needed which samples all of the workplace contaminants. It is also essential that the developed analytical procedure meet the stringent requirements of the Data Quality Act (DQA) of 2001. This project aims to develop needed analytical methodology for MWF and to study the performance of that methodology among multiple laboratories such that data obtained using that methodology meets the quality and transparency criteria of the DQA. Successful performance testing of the method, conducted in accord with ASTM requirements, will provide significant support for national and international usage of the technology. This performance testing will also be used to provide participants with feedback to non-conforming laboratories so that corrective action may be taken. Pending outcome of the performance testing, the technology developed may be transferred to an NGO such as AIHA for implementation of routine liquid aerosol performance testing as part of its overall proficiency testing program. The analytical method(s) will be published for field usage in NMAM and the results of the performance studies in the relevant industrial hygiene literature. As this project addresses these needs, it supports Goal 2.3 of the Exposure Assessment Coordinated Emphasis Area which calls for improved methods for assessing environmental exposure to workplace chemicals. This should significantly improve the understanding of occupational risks involved in use of MWF. Use of these methods should make it possible to reduce the incidence and severity of respiratory effects of inhaled MWF, thus addressing the Respiratory Disease Strategic Goal 1 to prevent and reduce work-related airways disease and respiratory malignancies.
An informal survey of industrial hygiene equipment suppliers and AIHA accredited laboratories could be conducted to substantiate the magnitude of the use the new sampling device by industrial hygienists and analytical methods by laboratories for the assessment of MWF workers' exposures.
There are approximately 2 million workers exposed to metalworking Fluids (MWF) in the United States. Metalworking fluids (MWFs) lubricate, cool, and remove debris from the work surfaces of metal parts that are being drilled, ground, milled, or turned. They are generally classified according to the amount of mineral oil that they contain. Straight fluids primarily contain mineral oil. The three other types of MWF are all mixed with water prior to use. They include soluble fluids that contain up to 80% mineral oil, semisynthetic fluids that contain up to 40% mineral oil, and synthetic fluids that contain no mineral oil. Water-mixed fluids may also contain alkanolamines, biocides, boron compounds, and emulsifiers as well as ionic and nonionic surfactants.