Before reviewing treatment options, we must first start with identifying the sites at which bleeding might occur. Most children with hemophilia present as babies or toddlers, when crawling, walking, falling, and climbing occur. Presenting signs may include bleeding from circumcision, excessive bruising, mouth bleeding, bleeding from heel sticks, or swelling in a muscle or soft tissue. Bleeding can occur at various sites of the body with complications that depend on the site of bleeding. Bleeding sites fall into three categories: life-threatening, common, and other sites.