HIV Screening & Testing
The listed documents provide guidance about HIV screening and diagnostic
testing of patients and clients and HIV screening of donated tissue and organs.
This guidance is intended for clinicians and other HIV testing providers. HIV screening and testing guidance continues to evolve with changes in testing technology and methods to reach persons who can benefit from these services. Currently, CDC is updating recommendations for HIV testing outside of healthcare facilities and diagnostic HIV testing in laboratories in collaboration with federal and non-federal partner organizations. These recommendations will be posted on this page in the future.
- Revised Recommendations for HIV Testing of Adults, Adolescents, and Pregnant Women In Health-Care Settings, MMWR 2006
- HIV Testing Implementation Guidance for Correctional Settings, 2009
- Revised Guidelines for HIV Counseling, Testing, and Referral, MMWR 2001
- Sexually Transmitted Diseases Treatment Guidelines, MMWR 2010
Donors of Blood, Organs and Other Tissues
- 2013 PHS Guideline for Reducing Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus Transmission Through Organ Transplantations
Laboratory Testing Recommendations
The document “Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations” updates recommendations for HIV testing by laboratories in the United States and offers approaches for reporting test results to persons ordering HIV tests and to public health authorities. In brief, testing begins with a combination immunoassay that detects HIV-1 and HIV-2 antibodies and HIV-1 p24 antigen. All specimens reactive on this initial assay undergo supplemental testing with an immunoassay that differentiates HIV-1 from HIV-2 antibodies. Specimens that are reactive on the initial immunoassay and nonreactive or indeterminate on the antibody differentiation assay proceed to HIV-1 nucleic acid testing for resolution.
- NEW! Laboratory Testing for the Diagnosis of HIV Infection: Updated Recommendations
- NEW! Quick Reference: Recommended Laboratory HIV Testing Algorithm for Serum or Plasma Specimens
- APHL Suggested Reporting Language