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Guideline for the Prevention and Control of Norovirus Gastroenteritis Outbreaks in Healthcare Settings, 2011

Table 3. Test Characteristics for Norovirus in Fecal Specimens

Diagnostic method Reference standard Quantity and type of evidence Findings*
Sensitivity (%) Specificity (%) PPV (%) NPV (%)

Kaplan criteria

PCR

1 DIAG 116

68

99

97

82

EIA/ELISA

PCR

10 DIAG 17,118-120,123-128
,139

31 – 90

65 – 100

52 – 100

56-97

EM

PCR

2 DIAG 17,119

24 – 58

98-99

88-94

71-91

NASBA

PCR

1 DIAG 144

100

50

-

-

* Range from studies that reported test characteristics
Negative predictive Value, NPV; Positive predictive value, PPV

Table 4. Kaplan Criteria[16]

  1. Vomiting in more than half of symptomatic cases
  2. Mean (or median) incubation period of 24 to 48 hours
  3. Mean (or median) duration of illness of 12 to 60 hours
  4. No bacterial pathogen isolated in stool culture

 

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