Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008
Table 7. Minimum cycle times for steam sterilization cycles
|Type of sterilizer||Item||Exposure time at 250oF (121oC)||Exposure time at 270oF (132oC)||Drying time|
|Gravity displacement||Wrapped instruments||30 min||15 min||15-30 min|
|Textile packs||30 min||25 min||15 min|
|Wrapped utensils||30 min||15 min||15-30 min|
|Dynamic-air-removal (e.g., prevacuum)||Wrapped instruments||4 min||20-30 min|
|Textile packs||4 min||5-20 min|
|Wrapped utensils||4 min||20 min|
Modified from Association for the Advancement of Medical Instrumentation. 813, 819.
Table 8. Examples of flash steam sterilization parameters.
|Type of sterilizer||Load configuration||Temperature||Time|
|Gravity displacement||Nonporous items only (i.e., routine metal instruments, no lumens)||132°C (270°F)||3 minutes|
|Nonporous and porous items (e.g., rubber or plastic items, items with lumens) sterilized together||132°C (270°F)||10 minutes|
|Prevacuum||Nonporous items only (i.e., routine metal instruments, no lumens)||132°C (270°F)||3 minutes|
|Nonporous and porous items (e.g., rubber or plastic items, items with lumens) sterilized together||132°C (270°F)||4 minutes|
|Steam-flush pressure-pulse||Nonporous or mixed nonporous/porous items||
Modified from Association for the Advancement of Medical Instrumentation. 812, 819.
Table 9. Characteristics of an ideal low-temperature sterilization process.
High efficacy: the agent should be virucidal, bactericidal, tuberculocidal, fungicidal and sporicidal Rapid activity: ability to quickly achieve sterilization
Strong penetrability: ability to penetrate common medical-device packaging materials and penetrate into the interior of device lumens
Material compatibility: produces only negligible changes in the appearance or the function of processed items and packaging materials even after repeated cycling
Nontoxic: presents no toxic health risk to the operator or the patient and poses no hazard to the environment
Organic material resistance: withstands reasonable organic material challenge without loss of efficacy
Adaptability: suitable for large or small (point of use) installations
Monitoring capability: monitored easily and accurately with physical, chemical, and biological process monitors
Cost effectiveness: reasonable cost for installation and for routine operation
Modified from Schneider. 851