Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Diagnosis and Management of Chronic Fatigue Syndrome


The Diagnosis and Management of Chronic Fatigue Syndrome (CFS) course is a web-based training course designed to teach clinicians and other healthcare professionals about the background, epidemiology, diagnosis, and management of CFS. Lesson 1 provides an overview and definition of CFS. Lesson 2 teaches about making a diagnosis of CFS. Lesson 3 reviews possible triggers or causes of CFS and Lesson 4 gives an overview of management strategies. Lesson 5 discusses the impact of CFS. After the lessons, two clinical case studies will be presented.

Technical Requirements

To run this course your browser must support frames and Javascript.

Instructions for Completing Posttest & Evaluation Online

  1. View the Diagnosis and Management of Chronic Fatigue Syndrome (CFS) course online.
  2. Once you completed the course, go to CDC Training and Continuing Education Online at
    1. If you have not registered as a participant, click on new participant to create a user ID and password; otherwise click on participant login and login.
    2. If you have registered in this system before, please use the same login name and password. This will ensure an accurate transcript.
  3. Once you have logged in/registered, Click on search and keyword search for course WB1888.
  4. Click on the course. The course information page will come up. Scroll down to register here. Click on the type of CE credit that you would like to receive and then submit. Three demographic questions will come up. Complete the questions and then submit.
  5. From "Participant services," click on "evaluations and tests"
  6. Answer the questions presented on posttest (all answers are in the course material).
    1. To receive continuing education credit, you must answer all of the questions.
    2. Some questions have more than one answer. Questions with more than one answer will instruct you to "indicate all that are correct."
  7. Complete the course evaluation.
  8. You will be able to immediately print your continuing education certificate from your personal transcript.
  9. A record of your completion will be located in the transcript and certificate section of your record.
  10. If you have any questions or problems contact CDC Training and Continuing Education Online at: 1-800-41TRAIN or 404-639-1292 or

Origination Date: 06/27/2012
Expiration Date: 06/27/2016

Course Objectives

After completing this course you will be able to:

  1. Define CFS according to the 1994 Case Definition and discuss other definitions.
  2. Explain the diagnostic process for chronic fatigue syndrome.
  3. Discuss possible triggers, contributing factors, and physiology of CFS.
  4. Identify management strategies in CFS.
  5. Recognize the wide-ranging impact of CFS.

Target Audience

The Diagnosis and Management of Chronic Fatigue Syndrome (CFS) is intended for the following clinicians who desire a basic introduction to CFS diagnosis, and management:

  • Nurses
  • Nurse practitioners
  • Physician assistants
  • Physicians
  • Medical Students
  • Dentists
  • Psychologists
  • Occupational Therapists
  • Health Educators


There are no prerequisites for this course.

Accreditation Statements

Students completing the Diagnosis and Management of Chronic Fatigue Syndrome (CFS) course can earn continuing education credits/contact hours in one of the following categories:

Continuing Medical Education (CME)

The Centers for Disease Control and Prevention is accredited by the Accreditation Council for Continuing Medical Education (ACCME®) to provide continuing medical education for physicians.

The Centers for Disease Control and Prevention designates this enduring activity for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Continuing Nursing Education (CNE):

The Centers for Disease Control and Prevention is accredited as a provider of Continuing Nursing Education by the American Nurses Credentialing Center's Commission on Accreditation.

This activity provides 1.0 contact hours.

IACET Continuing Education Units (CEU)

The Centers for Disease Control and Prevention is authorized by IACET to offer 0.1 CEU's for this program.

Continuing Education Contact Hours

Sponsored by the Centers for Disease Control and Prevention, a designated provider of continuing education contact hours (CECH) in health education by the National Commission for Health Education Credentialing, Inc. This program is designed for Certified Health Education Specialists (CHES) to receive up to 1.0 Category I CECH in health education. CDC provider number GA0082.

To obtain continuing education credit/contact hours, go to CDC/ATSDR Training and Continuing Education Online after completing the content of this module and register for course WB1888. You will be required to complete a posttest in order to obtain the credit or contact hours.

Disclosure Statement

CDC, our planners, and our content experts wish to disclose they have no financial interests or other relationships with the manufacturers of commercial products, suppliers of commercial services, or commercial supporters with the exception of Dr. Lucinda Bateman and she wishes to disclose the following relevant financial relationships: served as a speaker for Eli Lilly and Company; Forest Laboratories, Inc; and Pfizer Inc; and served as a principal investigator: Eli Lilly and Company; Forest Laboratories, Inc.; Hemispherx Biopharma, Inc; Pfizer Inc. Presentations will not include any discussion of the unlabeled use of a product or a product under investigational use. There is no commercial support for this activity.

Support/Funding: This program was developed solely by CDC.

Fees: No fees are charged for CDC's CE activities

Author/Developer Information

Course Developers and Subject Matter Experts

James F. Jones, MD
Medical Research Officer, Centers for Disease Control and Prevention

Lucinda Bateman, MD, MS
Director, Fatigue Consultation Clinic

Nancy Klimas, MD
Professor of Medicine, Nova Southeastern University

Connie Luedtke, RN
Nursing Supervisor Mayo Clinic Fibromyalgia and Chronic Fatigue Clinic,
Mayo Clinic

Ann Vincent, MD
Assistant Professor of Medicine
Mayo Clinic


Dana Brimmer, PhD, MPH

Sharon Hall, PhD, RN

Andy Miller, MD

Trang Nguyen, MPH, CHES

Elizabeth Unger, MD, PhD

Contact Information

For assistance with registration, completing the course assessment and posttest, transcripts, and printing continuing education certificates, please contact OWCD Training and Continuing Education. OWCD can be reached via:



Phone: 1-800-41-TRAIN (Monday- Friday 8:00am-4:00pm ET)

Fax: 404-498-6045

Please email with any questions regarding this course.

Continuing Educaiton Policies


CDC has no advertising within the educational content of CME activities on the internet or included within enduring materials. This includes, but not limited to, banner ads, subliminal ads, and pop-up window ads. See Training and Continuing Education OnLine (TCEO) disclaimer.

Policy on Privacy and Confidentiality

The Continuing Education Accreditation and Learner Support (CEALS) office at the Centers for Disease Control and Prevention (CDC) is committed to protecting the privacy and confidentiality of its customers. All information is locked and secured per CDC's policies. CEALS keeps only information necessary to provide you with the participant services necessary to honor your request for Continuing Education.

The CDC maintains its internet site as an information resource and to provide participants a platform to evaluate CE activities, receive a certificate, and print-out an on-going transcript of all their TCEO CE credits/contact hours.

The CDC site provides links to Policies and Regulations, which contain the Privacy Policy and Privacy Rules for government information. Use of Cookies; Privacy Rule, Legislation and Regulation, Additional Information; Accessibility, Report an accessibility problem, Section 508, and Assistance with accessing CDC information. There is a link to Web Site Disclaimers.


CDC is a federal government public health agency. In general all information presented and all items are available for download and for public use. This information is identified at Policies and Regulations; please see Guidelines for Ensuring the Quality of Information Disseminated to the Public.


CDC 24/7 – Saving Lives, Protecting People, Saving Money. Learn More About How CDC Works For You…
Contact Us:
  • Centers for Disease Control and Prevention
    1600 Clifton Rd
    Atlanta, GA 30333
  • 800-CDC-INFO
    TTY: (888) 232-6348
  • Contact CDC-INFO The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30329-4027, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC-INFO